ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: HSE1_1OEB-5.PDB
Scoring matrix: HSE1_1OEB-5_mat
Uniprot code: P38753
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 17.83
Foldx random average score for Saccharomyces cerevisiae: 21.292

Available information for P38753 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 49
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2079
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5100
 Total fragments: 2183615
Proteins after random average filtering: 5100
 Total fragments: 1077417
Proteins after disorder filtering: 3170
 Total fragments: 78800
Proteins after pattern filtering: 1599
 Total fragments: 13976
Proteins after MINT filtering: 19
 Total fragments: 491


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

17.83

2.32

0.00

Best peptides

MRRRRPRPHW

0.00

-6.83

-9.15

         
Interactors      
Q06604

MKNKPKPTPP

8.61

-7.87

-10.19

TMKNKPKPTP

11.31

-6.77

-9.09

RYSNIPSSKP

11.41

-9.15

-11.47

Q06108

LKSTDPPPQP

10.20

-6.57

-8.89

INMPIPKKLP

12.80

-6.67

-8.99

PRSPYYINMP

13.72

-7.91

-10.23

P40073

QFDGYPQQQP

14.02

-6.35

-8.67

GYPQQQPSHT

18.07

-3.63

-5.95

DGYPQQQPSH

21.14

-0.15

-2.47

P25604

PKPKSPHLKP

9.75

-7.18

-9.50

LKPPLPPPPP

9.96

-7.73

-10.05

PHLKPPLPPP

10.74

-8.75

-11.07

P40325

SQPRPPPRPQ

11.78

-6.20

-8.52

QNPSLPWTYP

12.76

-5.58

-7.90

PWTYPPRFYC

13.06

-5.43

-7.75

O13527

GKKLRAPGQP

11.19

-7.64

-9.96

PYQMSPMYFP

11.34

-5.04

-7.36

NSKIHPRGIP

11.58

-6.13

-8.45

P48524

DSGFPPKRKP

11.95

-6.83

-9.15

PLLRPQRSDF

13.08

-9.85

-12.17

RKPLLRPQRS

15.79

-8.60

-10.92

Q06412

VKERRPPPPP

6.45

-9.04

-11.36

FFTKPPPPLS

11.23

-6.71

-9.03

RRPPPPPPLL

11.63

-9.14

-11.46

Q66RC5

ISNPSPLIPD

15.30

-5.27

-7.59

PSPLIPDNPG

16.97

-2.91

-5.23

LIPDNPGRLL

18.76

-5.51

-7.83

P36037

EDGKPPLKLP

14.88

-4.20

-6.52

GKPPLKLPIN

18.03

-6.22

-8.54

PPLKLPINVS

20.21

-3.47

-5.79

P36041

LRPVIPRGPS

10.55

-5.36

-7.68

QQYMPPPPPP

11.00

-5.71

-8.03

FGSNSPMPIP

11.23

-6.52

-8.84

Q04439

RHSKKPAPPP

10.46

-8.30

-10.62

HSKKPAPPPP

10.51

-7.69

-10.01

QANIPPPPPP

11.13

-7.70

-10.02

P53901

MRPIPPLPTE

9.09

-7.52

-9.84

SGLNSPKLPP

11.91

-6.08

-8.40

HNYNQPPLPP

12.31

-5.76

-8.08

Q12446

TKHKAPPPPP

8.09

-8.26

-10.58

RRGPAPPPPP

8.82

-9.61

-11.93

PRRGPAPPPP

9.52

-8.87

-11.19

P40453

LRKRPPPPPP

5.16

-10.20

-12.52

RLRKRPPPPP

6.39

-12.48

-14.80

IRLRKRPPPP

7.54

-8.95

-11.27

P40343

LAPSDPPYPK

13.09

-5.02

-7.34

PQQPSPQPQP

14.41

-3.13

-5.45

HVELAPSDPP

15.76

-5.83

-8.15

Q03497

HKQHKPKVKP

9.75

-9.31

-11.63

LKQTHAPTTP

9.98

-6.59

-8.91

VKKSFPSKNP

11.71

-8.42

-10.74

P53238

GRPIPPAPTH

12.71

-5.25

-7.57

QKPAGRPIPP

13.58

-5.95

-8.27

AGRPIPPAPT

14.12

-5.06

-7.38

P40041

KIPLSPPSSS

16.63

-5.61

-7.93

PNGRTLPPVP

16.90

-6.61

-8.93

PLSPPSSSNM

19.04

-4.48

-6.80

 


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