ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: HSE1_1OEB-4.PDB
Scoring matrix: HSE1_1OEB-4_mat
Uniprot code: P38753
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 28.73
Foldx random average score for Saccharomyces cerevisiae: 25.835

Available information for P38753 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 49
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2079
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5100
 Total fragments: 2183615
Proteins after random average filtering: 5100
 Total fragments: 894285
Proteins after disorder filtering: 3081
 Total fragments: 53050
Proteins after pattern filtering: 1485
 Total fragments: 8523
Proteins after MINT filtering: 20
 Total fragments: 330


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

28.73

5.92

0.00

Best peptides

KRPRKQRKPR

0.00

-1.79

-7.71

         
Interactors      
Q07660

TPSAFKPIGP

23.22

-1.44

-7.36

Q06604

MKNKPKPTPP

13.31

-7.04

-12.96

EKGPRMPSRG

19.31

-4.56

-10.48

NKPKPTPPSP

20.06

-3.40

-9.32

Q06108

PRSPYYINMP

12.40

-7.34

-13.26

IRTPCKSPYS

15.94

-3.41

-9.33

GGISKQPATP

19.54

-3.11

-9.03

P40073

GYPQQQPSHT

20.79

-2.51

-8.43

DGYPQQQPSH

22.04

0.76

-5.16

FDGYPQQQPS

25.46

-0.94

-6.86

P25604

KPKSPHLKPP

16.70

-4.92

-10.84

KSPHLKPPLP

17.67

-6.87

-12.79

LKPPLPPPPP

20.72

-6.50

-12.42

P40325

HQSRPHQRPS

12.98

-6.07

-11.99

SLPWTYPPRF

15.61

-0.64

-6.56

QRPSTMPATS

16.03

-5.72

-11.64

O13527

PRGIPGYALH

17.74

-5.25

-11.17

QMSPMYFPPG

18.07

-2.95

-8.87

PQNGPYPQQC

18.50

-1.78

-7.70

P48524

PLLRPQRSDF

11.50

-3.52

-9.44

SGFPPKRKPL

19.77

-3.08

-9.00

KRKPLLRPQR

21.45

-4.74

-10.66

Q06412

VKERRPPPPP

15.55

-7.94

-13.86

KERRPPPPPP

18.88

-8.52

-14.44

ERRPPPPPPL

18.90

-6.05

-11.97

Q66RC5

PLIPDNPGRL

22.05

-1.83

-7.75

IPDNPGRLLS

22.65

-7.42

-13.34

P36037

GKPPLKLPIN

19.34

-2.21

-8.13

P36041

PLPQGFPIPP

16.60

-4.24

-10.16

AHQGPQFPVM

16.72

-3.67

-9.59

PPNFPQRMMP

16.76

-5.32

-11.24

Q04439

SRHSKKPAPP

12.59

-7.43

-13.35

KKPAPPPPGM

19.49

-4.15

-10.07

PKEPMFEAAY

20.26

-0.95

-6.87

P53901

SHNYNQPPLP

15.89

-5.07

-10.99

PNSHPHPSGL

19.50

-5.52

-11.44

MRPIPPLPTE

19.93

-6.92

-12.84

Q12446

NRPLPQLPNR

12.55

-2.45

-8.37

PRRGPAPPPP

16.27

-9.15

-15.07

TNPFPFPVPQ

16.52

-2.45

-8.37

P40453

IRLRKRPPPP

9.51

-9.26

-15.18

LRKRPPPPPP

14.70

-12.36

-18.28

KRPPPPPPVS

16.74

-5.44

-11.36

P40343

QQPSPQPQPI

13.56

-3.98

-9.90

PSPQPQPIHS

21.68

-0.91

-6.83

ELAPSDPPYP

21.82

-1.92

-7.84

Q03497

HKPKVKPSKP

13.12

-7.31

-13.23

KQHKPKVKPS

14.23

-7.79

-13.71

SRPAPKPPSS

16.65

-3.71

-9.63

P53238

QKPAGRPIPP

17.95

-5.82

-11.74

GRPIPPAPTH

21.30

-4.70

-10.62

KPAGRPIPPA

24.95

-5.03

-10.95

P40041

PLSPPSSSNM

25.24

-0.86

-6.78

 


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