ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: HSE1_1OEB-28.PDB
Scoring matrix: HSE1_1OEB-28_mat
Uniprot code: P38753
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 18.48
Foldx random average score for Saccharomyces cerevisiae: 14.862

Available information for P38753 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 49
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2079
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5100
 Total fragments: 2183615
Proteins after random average filtering: 5100
 Total fragments: 1065626
Proteins after disorder filtering: 2964
 Total fragments: 45009
Proteins after pattern filtering: 1438
 Total fragments: 7656
Proteins after MINT filtering: 18
 Total fragments: 272


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

18.48

-1.95

0.00

Best peptides

FPRIHRRPKR

0.00

-10.29

-8.34

         
Interactors      
Q06604

KPLLPTRPNK

7.41

-11.80

-9.85

NEEKPLLPTR

8.17

-9.08

-7.13

FEKGPRMPSR

8.97

-9.27

-7.32

Q06108

STDPPPQPRR

9.23

-9.41

-7.46

PPPQPRRLSD

9.75

-9.02

-7.07

DPPPQPRRLS

10.70

-9.18

-7.23

P25604

LPPKPKSPHL

9.70

-9.63

-7.68

TPPLPPKPKS

10.80

-9.95

-8.00

LPPKPNTQLQ

11.21

-9.31

-7.36

P40325

QPPRPPRPAA

7.06

-12.06

-10.11

QPRPPPRPQQ

7.20

-10.82

-8.87

QSRPHQRPST

10.23

-9.06

-7.11

O13527

NVPLNPKGKK

9.31

-10.91

-8.96

PLNPKGKKLR

9.39

-9.62

-7.67

KIHPRGIPGY

10.66

-8.26

-6.31

P48524

FPPKRKPLLR

5.83

-10.02

-8.07

KRKPLLRPQR

6.72

-9.40

-7.45

GFPPKRKPLL

10.97

-8.31

-6.36

Q06412

KPPPPLSTSR

8.62

-9.94

-7.99

RPPPPPPLLY

9.34

-10.01

-8.06

NSPKSPRDSS

10.06

-6.78

-4.83

Q66RC5

SPLIPDNPGR

8.88

-10.34

-8.39

IPDNPGRLLS

10.20

-10.05

-8.10

LIPDNPGRLL

12.68

-9.42

-7.47

P36037

PPLKLPINVS

12.87

-8.19

-6.24

KPPLKLPINV

13.17

-10.44

-8.49

GKPPLKLPIN

13.71

-7.18

-5.23

P36041

MGVPPNFPQR

8.57

-11.40

-9.45

MPPPPGLVQF

9.10

-11.33

-9.38

FPMHPNFPNG

9.22

-11.16

-9.21

Q04439

RPSPPTAATR

9.15

-10.89

-8.94

KPKEPMFEAA

10.28

-10.88

-8.93

APPPPGMQNK

10.45

-10.48

-8.53

P53901

QPPLPPIPTR

7.50

-9.94

-7.99

LPPIPTRDDM

7.66

-9.92

-7.97

MRPIPPLPTE

9.50

-7.70

-5.75

Q12446

APPPPPRASR

5.87

-11.56

-9.61

LPQLPNRNNR

6.66

-13.71

-11.76

LPAPPPPPRR

7.73

-11.76

-9.81

P40453

KPPDLPIRLR

8.31

-9.87

-7.92

PPDLPIRLRK

8.98

-14.59

-12.64

PDLPIRLRKR

9.62

-10.52

-8.57

P40343

QPSPQPQPIH

11.28

-8.34

-6.39

APSDPPYPKE

12.06

-8.53

-6.58

PSPQPQPIHS

14.18

-5.84

-3.89

Q03497

FPSKNPLKNS

8.05

-8.60

-6.65

LPPIPPTKSK

8.24

-10.44

-8.49

QHKPKVKPSK

9.04

-7.80

-5.85

P53238

IPPAPTHYNN

9.04

-9.50

-7.55

RPIPPAPTHY

10.53

-10.19

-8.24

GRPIPPAPTH

11.85

-7.28

-5.33

P40041

KIPLSPPSSS

12.86

-7.53

-5.58

IPLSPPSSSN

13.59

-7.56

-5.61

PLSPPSSSNM

14.29

-7.48

-5.53

 


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