ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: HSE1_1OEB-26.PDB
Scoring matrix: HSE1_1OEB-26_mat
Uniprot code: P38753
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 15.99
Foldx random average score for Saccharomyces cerevisiae: 12.699

Available information for P38753 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 49
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2079
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5100
 Total fragments: 2188715
Proteins after random average filtering: 5099
 Total fragments: 862982
Proteins after disorder filtering: 3020
 Total fragments: 50622
Proteins after pattern filtering: 1583
 Total fragments: 12812
Proteins after MINT filtering: 20
 Total fragments: 522


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

15.99

-1.64

0.00

Best peptides

DDRPRRPPR

0.00

-8.65

-7.01

         
Interactors      
Q07660

PSAFKPIGP

12.52

-5.62

-3.98

Q06604

EEKPLLPTR

4.91

-10.28

-8.64

SSPPPLPTR

4.93

-10.16

-8.52

EKGPRMPSR

5.15

-9.72

-8.08

Q06108

TDPPPQPRR

4.17

-9.53

-7.89

DPPPQPRRL

7.71

-8.44

-6.80

STDPPPQPR

7.83

-6.53

-4.89

P40073

GYPQQQPSH

8.47

-7.51

-5.87

DGYPQQQPS

10.86

-6.28

-4.64

P25604

DQAPSLPPK

6.52

-9.39

-7.75

PLPPPPPPQ

6.98

-8.48

-6.84

TPPLPPKPK

7.59

-7.74

-6.10

P40325

QSQPPRPPR

3.14

-11.47

-9.83

SSQPRPPPR

4.08

-8.07

-6.43

SLPWTYPPR

5.41

-8.07

-6.43

O13527

YGHPSMIPY

8.01

-7.77

-6.13

IHPRGIPGY

8.27

-7.33

-5.69

SAVPENPHH

8.75

-7.79

-6.15

P48524

RKPLLRPQR

4.76

-11.37

-9.73

PPKRKPLLR

7.07

-6.72

-5.08

GFPPKRKPL

7.36

-10.17

-8.53

Q06412

ERRPPPPPP

5.96

-7.45

-5.81

RRPPPPPPL

6.87

-8.13

-6.49

KERRPPPPP

7.66

-6.64

-5.00

Q66RC5

PLIPDNPGR

9.36

-7.72

-6.08

PDNPGRLLS

10.54

-8.46

-6.82

LIPDNPGRL

11.67

-4.43

-2.79

P36037

GKPPLKLPI

8.72

-7.79

-6.15

DGKPPLKLP

9.82

-8.03

-6.39

KPPLKLPIN

10.82

-7.63

-5.99

P36041

DLRPVIPRG

6.26

-9.16

-7.52

GVPPNFPQR

6.49

-8.18

-6.54

TPPPPPPGL

7.35

-7.77

-6.13

Q04439

PPPPGMQNK

7.02

-8.53

-6.89

SKKPAPPPP

7.68

-7.84

-6.20

KPAPPPPGM

7.76

-7.40

-5.76

P53901

PPLPPIPTR

6.89

-9.88

-8.24

AMRPIPPLP

8.17

-6.41

-4.77

MAMRPIPPL

8.28

-8.42

-6.78

Q12446

PAPPPPPRR

4.74

-9.33

-7.69

PAPPPPPHR

4.91

-9.72

-8.08

PPPPPRASR

5.17

-11.40

-9.76

P40453

EIPPPLPPK

5.33

-9.56

-7.92

PDLPIRLRK

6.48

-9.99

-8.35

WKPPDLPIR

6.54

-10.05

-8.41

P40343

PSPQPQPIH

8.42

-6.81

-5.17

ELAPSDPPY

8.75

-7.33

-5.69

APSDPPYPK

8.79

-4.32

-2.68

Q03497

PLPPIPPTK

5.92

-8.28

-6.64

THAPTTPNR

6.93

-8.45

-6.81

HKPKVKPSK

7.05

-8.89

-7.25

P53238

AGRPIPPAP

7.99

-6.82

-5.18

QKPAGRPIP

9.81

-8.97

-7.33

RPIPPAPTH

10.01

-7.21

-5.57

P40041

NGRTLPPVP

9.90

-6.34

-4.70

KIPLSPPSS

10.10

-6.45

-4.81

 


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