ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: HSE1_1OEB-23.PDB
Scoring matrix: HSE1_1OEB-23_mat
Uniprot code: P38753
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 11.7
Foldx random average score for Saccharomyces cerevisiae: 11.579

Available information for P38753 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 49
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2079
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5100
 Total fragments: 2198915
Proteins after random average filtering: 5100
 Total fragments: 1215176
Proteins after disorder filtering: 3457
 Total fragments: 103483
Proteins after pattern filtering: 1652
 Total fragments: 12621
Proteins after MINT filtering: 19
 Total fragments: 487


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

11.70

-0.50

0.00

Best peptides

RPRPPYP

0.00

-1.91

-1.41

         
Interactors      
Q07660

AFKPIGP

6.78

-2.15

-1.65

Q06604

KPKPTPP

2.90

-3.58

-3.08

RVKPAPP

3.16

-4.67

-4.17

KPTPPSP

3.54

-3.44

-2.94

Q06108

KTDPRSP

4.09

-3.00

-2.50

PRSPYYI

6.78

-1.68

-1.18

TDPPPQP

6.79

-1.94

-1.44

P25604

HLKPPLP

4.35

-3.64

-3.14

PPLPPKP

4.57

-3.62

-3.12

LPPPPPP

4.71

-3.92

-3.42

P40325

PPRPPRP

4.01

-3.56

-3.06

RPPPRPQ

4.13

-3.95

-3.45

QPRPPPR

4.95

-4.25

-3.75

O13527

LPLPDLP

4.15

-4.03

-3.53

MYFPPGP

4.80

-3.58

-3.08

MSPMYFP

4.95

-5.20

-4.70

P48524

RKPLLRP

6.39

-6.85

-6.35

KPLLRPQ

6.56

-6.21

-5.71

FPPKRKP

7.98

-5.59

-5.09

Q06412

RPPPPPP

2.62

-4.60

-4.10

RRPPPPP

2.76

-5.29

-4.79

ERRPPPP

4.30

-2.61

-2.11

Q66RC5

NPSPLIP

6.44

-2.01

-1.51

PLIPDNP

7.46

-1.95

-1.45

PDNPGRL

8.12

-2.18

-1.68

P36037

KPPLKLP

6.61

-6.06

-5.56

PPLKLPI

8.78

-3.78

-3.28

PLKLPIN

10.43

-4.57

-4.07

P36041

RMMPPPP

1.86

-5.36

-4.86

MPPPPPP

3.82

-4.32

-3.82

QPQPPYP

4.34

-2.75

-2.25

Q04439

KPAPPPP

3.63

-2.96

-2.46

NARPSPP

4.88

-3.08

-2.58

IPPPPPP

5.09

-2.88

-2.38

P53901

RPIPPLP

2.62

-4.92

-4.42

PPLPPIP

4.66

-3.25

-2.75

PKLPPLP

5.12

-3.74

-3.24

Q12446

RPLPQLP

2.12

-6.29

-5.79

RPVPPPP

3.07

-5.28

-4.78

KAPPPPP

3.55

-3.50

-3.00

P40453

RKRPPPP

1.19

-6.41

-5.91

RPPPPPP

2.62

-4.60

-4.10

KRPPPPP

3.17

-3.70

-3.20

P40343

PSDPPYP

5.29

-2.20

-1.70

SPQPQPI

7.15

-2.01

-1.51

QPSPQPQ

7.77

-0.91

-0.41

Q03497

KVKPSKP

3.42

-3.62

-3.12

RPAPKPP

3.48

-3.58

-3.08

KFIPSRP

3.73

-3.84

-3.34

P53238

RPIPPAP

2.99

-5.47

-4.97

AGRPIPP

5.30

-3.22

-2.72

KPAGRPI

5.79

-3.19

-2.69

P40041

RTLPPVP

2.89

-5.76

-5.26

KIPLSPP

7.40

-5.50

-5.00

IPLSPPS

8.44

-3.71

-3.21

 


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