ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: HSE1_1OEB-21.PDB
Scoring matrix: HSE1_1OEB-21_mat
Uniprot code: P38753
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAGGAAAA
Foldx wt ligand score: 19.81
Foldx random average score for Saccharomyces cerevisiae: 17.781

Available information for P38753 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 49
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2079
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5100
 Total fragments: 2183615
Proteins after random average filtering: 5100
 Total fragments: 1214241
Proteins after disorder filtering: 3026
 Total fragments: 47671
Proteins after pattern filtering: 1159
 Total fragments: 3118
Proteins after MINT filtering: 18
 Total fragments: 99


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAGGAAAA

19.81

-0.89

0.00

Best peptides

EQRIGRPTWH

0.00

-4.40

-3.52

         
Interactors      
Q06604

EKGPRMPSRG

11.95

-4.54

-3.66

PLLPTRPNKA

13.23

-5.29

-4.41

PTPPSPPAKR

14.47

-6.27

-5.38

Q06108

KQPATPGSTR

14.50

-4.93

-4.04

SKQPATPGST

15.51

-4.48

-3.60

LPGVSPSCLA

16.12

-5.07

-4.19

P40073

GYPQQQPSHT

16.30

-3.13

-2.25

P25604

PPKPKSPHLK

11.65

-5.73

-4.85

SLPPKPNTQL

15.42

-4.20

-3.32

PPQPASNALD

16.83

-4.18

-3.29

P40325

YVQPGDPRLG

12.48

-6.70

-5.82

SRPHQRPSTM

13.67

-3.93

-3.04

LPWTYPPRFY

15.15

-5.57

-4.69

O13527

PLNPKGKKLR

11.13

-6.70

-5.82

LNVPLNPKGK

13.55

-3.70

-2.82

NVPLNPKGKK

13.98

-5.81

-4.92

P48524

RKPLLRPQRS

11.41

-6.56

-5.67

FPPKRKPLLR

14.75

-6.60

-5.71

KPLLRPQRSD

16.36

-4.61

-3.73

Q06412

PKSPRDSSKQ

13.29

-3.87

-2.99

PNSPKSPRDS

16.26

-5.01

-4.13

PPPPLSTSRN

16.90

-3.99

-3.11

Q66RC5

PLIPDNPGRL

14.21

-4.53

-3.65

LIPDNPGRLL

16.34

-5.49

-4.61

P36037

KPPLKLPINV

16.06

-3.62

-2.74

P36041

HQGPQFPVMG

11.74

-6.72

-5.84

QQTPGIPVGQ

12.78

-4.77

-3.88

PQPPYPNMML

13.05

-7.06

-6.17

Q04439

SSKPKEPMFE

12.48

-5.63

-4.75

NNIPTPPQNR

13.48

-4.31

-3.42

PPPPGMQNKA

15.45

-5.38

-4.50

P53901

DPIILPPTFS

12.41

-5.99

-5.11

PPIPTRDDMS

16.41

-2.04

-1.16

KLPPLPTTSN

16.52

-4.48

-3.60

Q12446

RPLPQLPNRN

13.92

-5.78

-4.90

PQMPATSTSG

14.00

-5.09

-4.21

FPIPEIPSTQ

14.91

-3.09

-2.21

P40453

TKVPEPPSWK

11.60

-5.10

-4.21

PDLPIRLRKR

12.38

-7.38

-6.50

WKPPDLPIRL

13.68

-5.26

-4.38

Q03497

PLPPIPPTKS

14.18

-4.95

-4.07

THAPTTPNRT

14.27

-5.67

-4.79

KVKPSKPEAK

15.84

-2.89

-2.00

P53238

PIPPAPTHYN

17.08

-3.35

-2.46

P40041

KIPLSPPSSS

17.13

-3.77

-2.88

 


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