ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: HSE1_1OEB-20.PDB
Scoring matrix: HSE1_1OEB-20_mat
Uniprot code: P38753
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 15.85
Foldx random average score for Saccharomyces cerevisiae: 17.969

Available information for P38753 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 49
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2079
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5100
 Total fragments: 2188715
Proteins after random average filtering: 5100
 Total fragments: 1061005
Proteins after disorder filtering: 3173
 Total fragments: 60098
Proteins after pattern filtering: 1412
 Total fragments: 5624
Proteins after MINT filtering: 19
 Total fragments: 198


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

15.85

-0.32

0.00

Best peptides

YPFRNRRRM

0.00

-8.58

-8.26

         
Interactors      
Q06604

GPRMPSRGR

10.11

-8.82

-8.50

PPSPPAKRI

11.42

-7.33

-7.01

PPLPTRRDH

11.62

-7.11

-6.79

Q06108

PPPQPRRLS

10.27

-7.18

-6.86

PPQPRRLSD

11.45

-5.84

-5.52

QPATPGSTR

12.71

-5.98

-5.66

P40073

GYPQQQPSH

14.62

-3.72

-3.40

P25604

PPKPKSPHL

12.45

-7.68

-7.36

LPPKPKSPH

12.69

-7.19

-6.87

LPPKPNTQL

13.45

-9.08

-8.76

P40325

RPPRPAANL

11.03

-7.96

-7.64

PPRPPRPAA

11.46

-6.12

-5.80

YVQPGDPRL

11.93

-7.43

-7.11

O13527

PLNPKGKKL

11.25

-7.46

-7.14

VPLNPKGKK

12.77

-5.82

-5.50

VPENPHHAS

13.52

-3.89

-3.57

P48524

FPPKRKPLL

8.88

-8.30

-7.98

GFPPKRKPL

12.32

-5.57

-5.25

RKPLLRPQR

12.72

-8.37

-8.05

Q06412

PPPPLSTSR

12.04

-7.68

-7.36

SPKSPRDSS

13.53

-3.58

-3.26

PKSPRDSSK

14.26

-3.99

-3.67

Q66RC5

IPDNPGRLL

10.03

-8.66

-8.34

PDNPGRLLS

17.24

-4.14

-3.82

PLIPDNPGR

17.34

-6.81

-6.49

P36037

KPPLKLPIN

14.49

-6.19

-5.87

GKPPLKLPI

16.79

-6.14

-5.82

P36041

PPPPPGLIA

12.53

-6.64

-6.32

PVIPRGPSS

12.79

-4.38

-4.06

PPLPQGFPI

12.99

-5.13

-4.81

Q04439

APPPPGMQN

13.73

-5.63

-5.31

PPPPSSKPK

14.05

-5.14

-4.82

SSKPKEPMF

14.74

-4.83

-4.51

P53901

PPIPTRDDM

13.97

-5.85

-5.53

RPIPPLPTE

14.73

-7.25

-6.93

SSSPNSHPH

15.03

-2.76

-2.44

Q12446

PPPPPRASR

9.16

-11.34

-11.02

PPPPPHRHV

11.84

-9.73

-9.41

RPLPQLPNR

12.14

-7.33

-7.01

P40453

PDLPIRLRK

11.50

-7.02

-6.70

DCPRCGPTA

13.59

-4.72

-4.40

WKPPDLPIR

14.20

-6.22

-5.90

P40343

PSPQPQPIH

15.28

-4.00

-3.68

PQPQPIHSV

17.08

-3.74

-3.42

PSDPPYPKE

17.54

-3.46

-3.14

Q03497

HKPKVKPSK

10.67

-6.38

-6.06

KPSKPEAKS

13.26

-6.00

-5.68

PSKPEAKSK

13.64

-3.91

-3.59

P53238

RPIPPAPTH

13.06

-7.89

-7.57

PPAPTHYNN

15.20

-4.79

-4.47

IPPAPTHYN

17.96

-4.87

-4.55

P40041

PLSPPSSSN

16.27

-4.53

-4.21

 


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