ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: HSE1_1OEB-19.PDB
Scoring matrix: HSE1_1OEB-19_mat
Uniprot code: P38753
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 12.97
Foldx random average score for Saccharomyces cerevisiae: 13.609

Available information for P38753 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 49
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2079
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5100
 Total fragments: 2188715
Proteins after random average filtering: 5100
 Total fragments: 1082567
Proteins after disorder filtering: 3198
 Total fragments: 69488
Proteins after pattern filtering: 1521
 Total fragments: 7390
Proteins after MINT filtering: 19
 Total fragments: 247


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

12.97

-0.25

0.00

Best peptides

SPLRNGKHM

0.00

-3.34

-3.09

         
Interactors      
Q06604

GPRMPSRGR

8.47

-6.40

-6.16

LPTRPNKAE

9.47

-5.27

-5.02

KPTPPSPPA

10.06

-4.52

-4.27

Q06108

TDPPPQPRR

8.72

-6.58

-6.34

KTDPRSPYY

8.72

-5.23

-4.99

QPATPGSTR

8.74

-1.84

-1.60

P40073

DGYPQQQPS

12.73

-3.89

-3.65

P25604

PPKPKSPHL

7.17

-6.65

-6.41

PPKPNTQLQ

9.11

-6.68

-6.43

PPLPPKPKS

9.13

-5.23

-4.99

P40325

RPPRPAANL

8.05

-7.76

-7.51

PRPPPRPQQ

9.86

-7.57

-7.33

YVQPGDPRL

10.01

-5.30

-5.05

O13527

PLNPKGKKL

6.66

-6.25

-6.00

MYFPPGPQS

9.18

-3.64

-3.40

VPLNPKGKK

9.18

-4.62

-4.38

P48524

FPPKRKPLL

8.40

-6.28

-6.04

KRKPLLRPQ

9.30

-6.36

-6.12

PLLRPQRSD

10.57

-6.72

-6.47

Q06412

PPPPLSTSR

9.89

-5.37

-5.13

SPNSPKSPR

10.28

-2.59

-2.34

KPPPPLSTS

10.47

-4.34

-4.09

Q66RC5

IPDNPGRLL

5.79

-3.95

-3.71

PLIPDNPGR

10.97

-4.85

-4.60

PDNPGRLLS

11.63

-3.73

-3.48

P36037

DGKPPLKLP

12.07

-6.02

-5.77

KPPLKLPIN

12.60

-5.19

-4.95

P36041

MPPPPGLVQ

6.51

-5.72

-5.47

PPPPPGLIA

7.71

-4.22

-3.97

PPYPNMMLQ

8.09

-6.54

-6.29

Q04439

APPPPGMQN

7.93

-4.49

-4.25

SSKPKEPMF

9.55

-5.16

-4.92

SGSPSELPL

10.07

-3.58

-3.34

P53901

RPIPPLPTE

10.35

-3.52

-3.27

LNSPKLPPL

10.45

-5.57

-5.33

PPLPPIPTR

10.76

-4.81

-4.56

Q12446

PPPPPHRHV

7.03

-7.98

-7.74

RPLPQLPNR

7.37

-6.17

-5.92

PPPPPRASR

8.70

-7.41

-7.17

P40453

PDLPIRLRK

8.73

-5.17

-4.92

DCPRCGPTA

9.83

-5.56

-5.31

WKPPDLPIR

10.94

-4.13

-3.88

P40343

ELAPSDPPY

11.47

-4.95

-4.71

PSDPPYPKE

11.97

-4.10

-3.85

Q03497

KPSKPEAKS

9.25

-5.72

-5.47

PPIPPTKSK

9.87

-6.31

-6.06

SFPSKNPLK

10.93

-1.57

-1.33

P53238

RPIPPAPTH

10.23

-4.15

-3.91

PPAPTHYNN

10.86

-4.67

-4.42

IPPAPTHYN

11.47

-3.08

-2.84

P40041

PLSPPSSSN

11.46

-5.09

-4.84

 


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