ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: HSE1_1OEB-18.PDB
Scoring matrix: HSE1_1OEB-18_mat
Uniprot code: P38753
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAAA
Foldx wt ligand score: 15.59
Foldx random average score for Saccharomyces cerevisiae: 14.501

Available information for P38753 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 49
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2079
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5100
 Total fragments: 2183615
Proteins after random average filtering: 5100
 Total fragments: 1002918
Proteins after disorder filtering: 3105
 Total fragments: 57161
Proteins after pattern filtering: 1462
 Total fragments: 7207
Proteins after MINT filtering: 19
 Total fragments: 242


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAAA

15.59

0.03

0.00

Best peptides

FRPIKSHWYY

0.00

-0.18

-0.21

         
Interactors      
Q06604

KPLLPTRPNK

9.16

-7.57

-7.60

KPTPPSPPAK

9.55

-5.23

-5.26

LLPTRPNKAE

9.71

-4.84

-4.87

Q06108

KTDPRSPYYI

8.68

-2.55

-2.58

QPATPGSTRS

9.42

-3.55

-3.58

PPPQPRRLSD

10.80

-5.26

-5.29

P40073

GYPQQQPSHT

13.89

-2.67

-2.70

P25604

LPPKPKSPHL

9.54

-5.67

-5.70

TPPLPPKPKS

10.21

-5.34

-5.37

APSLPPKPNT

11.37

-5.92

-5.95

P40325

LPWTYPPRFY

7.87

-5.61

-5.64

PWTYPPRFYC

9.89

-3.09

-3.12

RPSTMPATSS

10.75

-4.14

-4.17

O13527

FPQYPSSVGT

9.03

-4.09

-4.12

NVPLNPKGKK

9.51

-4.91

-4.94

KIHPRGIPGY

10.15

-3.63

-3.66

P48524

RKPLLRPQRS

8.88

-5.43

-5.46

KPLLRPQRSD

10.00

-6.39

-6.42

PLLRPQRSDF

11.66

-3.90

-3.93

Q06412

PPPPPPLLYS

11.04

-3.92

-3.95

KPPPPLSTSR

11.20

-4.89

-4.92

FTKPPPPLST

11.69

-2.58

-2.61

Q66RC5

SPLIPDNPGR

11.19

-5.18

-5.21

PLIPDNPGRL

13.39

-3.30

-3.33

P36037

KPPLKLPINV

8.66

-5.90

-5.93

PPLKLPINVS

14.37

-3.24

-3.27

P36041

PMPIPSIINA

8.99

-2.98

-3.01

RPVIPRGPSS

9.97

-5.72

-5.75

MPPPPPPGFF

10.29

-4.87

-4.90

Q04439

NIPTPPQNRD

11.17

-3.72

-3.75

PPPPPPPSSK

11.85

-4.06

-4.09

APPPPGMQNK

11.87

-3.48

-3.51

P53901

LPPIPTRDDM

9.99

-4.03

-4.06

IPPLPTESEY

10.52

-4.80

-4.83

DPIILPPTFS

11.48

-4.69

-4.72

Q12446

LPQLPNRNNR

8.67

-7.87

-7.90

LPAPPPPPRR

10.01

-6.22

-6.25

LPPASPEVRK

10.12

-3.49

-3.52

P40453

PPDLPIRLRK

10.03

-7.58

-7.61

RPPPPPPVSM

10.09

-4.83

-4.86

KVPEPPSWKP

11.21

-3.12

-3.15

P40343

APSDPPYPKE

11.51

-2.77

-2.80

SPQPQPIHSV

12.26

-2.94

-2.97

PSPQPQPIHS

13.20

-0.14

-0.17

Q03497

LPPIPPTKSK

8.60

-7.04

-7.07

FPSKNPLKNS

8.81

-6.30

-6.33

KPSKPEAKSK

9.42

-5.70

-5.73

P53238

RPIPPAPTHY

9.25

-3.88

-3.91

IPPAPTHYNN

12.10

-4.12

-4.15

PIPPAPTHYN

12.65

-3.95

-3.98

P40041

KIPLSPPSSS

10.69

-4.83

-4.86

PLSPPSSSNM

12.13

-1.63

-1.66

IPLSPPSSSN

12.52

-3.28

-3.31

 


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