ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: HSE1_1OEB-17.PDB
Scoring matrix: HSE1_1OEB-17_mat
Uniprot code: P38753
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 15.1
Foldx random average score for Saccharomyces cerevisiae: 18.778

Available information for P38753 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 49
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2079
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5100
 Total fragments: 2188715
Proteins after random average filtering: 5100
 Total fragments: 1106892
Proteins after disorder filtering: 3230
 Total fragments: 65762
Proteins after pattern filtering: 1459
 Total fragments: 6413
Proteins after MINT filtering: 19
 Total fragments: 208


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

15.10

1.89

0.00

Best peptides

YPFVRGRAR

0.00

-4.11

-6.00

         
Interactors      
Q06604

GPRMPSRGR

9.71

-6.11

-8.00

EKGPRMPSR

11.37

-3.75

-5.64

LPTRPNKAE

12.83

-3.85

-5.74

Q06108

QPATPGSTR

9.62

-5.72

-7.61

TDPPPQPRR

13.19

-6.45

-8.34

KTDPRSPYY

13.85

-2.73

-4.62

P40073

GYPQQQPSH

16.47

-2.56

-4.45

P25604

PPPPPQPAS

13.32

-2.12

-4.01

LPPKPKSPH

13.62

-5.23

-7.12

LPPKPNTQL

14.04

-5.86

-7.75

P40325

PPRPPRPAA

12.25

-3.09

-4.98

LYVQPGDPR

12.70

-3.15

-5.04

YVQPGDPRL

12.83

-3.89

-5.78

O13527

PLNPKGKKL

13.62

-3.65

-5.54

MYFPPGPQS

13.80

-2.17

-4.06

VPENPHHAS

13.86

-1.68

-3.57

P48524

FPPKRKPLL

9.64

-6.29

-8.18

PLLRPQRSD

12.91

-2.55

-4.44

RKPLLRPQR

14.54

-6.97

-8.86

Q06412

PPPPLSTSR

12.54

-5.28

-7.17

PKLPPLNTR

14.50

-3.18

-5.07

PKSPRDSSK

14.57

-2.73

-4.62

Q66RC5

IPDNPGRLL

11.46

-4.45

-6.34

PLIPDNPGR

15.42

-2.80

-4.69

P36037

GKPPLKLPI

17.48

-1.79

-3.68

KPPLKLPIN

18.25

-3.51

-5.40

P36041

PVIPRGPSS

11.96

-2.18

-4.07

PPNFPQRMM

12.00

-5.41

-7.30

GIPVGQPSL

12.65

-4.53

-6.42

Q04439

RPSPPTAAT

13.10

-2.68

-4.57

APPPPGMQN

14.73

-2.74

-4.63

PPPSSKPKE

15.17

-2.45

-4.34

P53901

PPLPPIPTR

13.08

-5.27

-7.16

YNQPPLPPI

14.21

-4.22

-6.11

RPIPPLPTE

14.26

-4.38

-6.27

Q12446

PPPPPRASR

10.12

-7.51

-9.40

APTTPAPAL

11.09

-3.28

-5.17

RPLPQLPNR

12.91

-6.02

-7.91

P40453

PPDLPIRLR

14.31

-4.64

-6.53

PDLPIRLRK

14.37

-4.16

-6.05

WKPPDLPIR

15.14

-3.06

-4.95

P40343

PSDPPYPKE

17.07

-0.86

-2.75

ELAPSDPPY

17.64

-0.79

-2.68

PQPQPIHSV

18.09

-1.32

-3.21

Q03497

HKPKVKPSK

12.90

-3.09

-4.98

LPGSPQVST

13.82

-1.77

-3.66

PPIPPTKSK

13.83

-4.81

-6.70

P53238

RPIPPAPTH

13.39

-5.48

-7.37

IPPAPTHYN

16.48

-3.28

-5.17

PPAPTHYNN

16.95

-2.73

-4.62

P40041

PLSPPSSSN

16.37

-2.56

-4.45

 


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