ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: HSE1_1OEB-16.PDB
Scoring matrix: HSE1_1OEB-16_mat
Uniprot code: P38753
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 20.39
Foldx random average score for Saccharomyces cerevisiae: 18.454

Available information for P38753 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 49
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2079
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5100
 Total fragments: 2188715
Proteins after random average filtering: 5100
 Total fragments: 981023
Proteins after disorder filtering: 3212
 Total fragments: 66004
Proteins after pattern filtering: 1468
 Total fragments: 6436
Proteins after MINT filtering: 19
 Total fragments: 201


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

20.39

0.75

0.00

Best peptides

HPPIKSKHF

0.00

-0.71

-1.46

         
Interactors      
Q06604

LPTRPNKAE

10.89

-4.28

-5.03

LLPTRPNKA

11.20

-5.85

-6.60

GPRMPSRGR

12.52

-6.16

-6.91

Q06108

RTPCKSPYS

11.91

-2.90

-3.65

PPPQPRRLS

12.98

-4.77

-5.52

KTDPRSPYY

14.06

-0.27

-1.02

P40073

FDGYPQQQP

17.63

-0.73

-1.48

P25604

TPPLPPKPK

12.67

-6.07

-6.82

PKPKSPHLK

15.41

-2.76

-3.51

APSLPPKPN

15.43

-4.92

-5.67

P40325

PWTYPPRFY

12.26

-1.71

-2.46

LPWTYPPRF

13.77

-6.06

-6.81

QPPRPPRPA

14.34

-6.05

-6.80

O13527

NVPLNPKGK

11.26

-1.45

-2.20

VPLNPKGKK

12.35

-3.19

-3.94

IPYTPYQMS

12.51

-4.57

-5.32

P48524

KPLLRPQRS

10.65

-5.87

-6.62

PPKRKPLLR

13.44

-4.79

-5.54

PLLRPQRSD

13.60

-4.27

-5.02

Q06412

NSPKSPRDS

13.31

-1.54

-2.29

PPPPPLLYS

13.69

-3.81

-4.56

FSPNSPKSP

15.50

-0.71

-1.46

Q66RC5

SPLIPDNPG

14.42

-3.63

-4.38

P36037

KPPLKLPIN

16.28

-4.64

-5.39

PLKLPINVS

16.38

-2.78

-3.53

P36041

PPPPPPGFF

12.09

-3.95

-4.70

FFPMHPNFP

12.30

-3.24

-3.99

RPVIPRGPS

13.24

-4.59

-5.34

Q04439

SKPKEPMFE

13.54

-1.65

-2.40

NIPTPPQNR

13.71

-3.01

-3.76

PPPPSSKPK

13.91

-1.23

-1.98

P53901

LPPIPTRDD

11.57

-3.91

-4.66

DPIILPPTF

14.73

-4.08

-4.83

IPPLPTESE

15.75

-4.29

-5.04

Q12446

LPPLPNQFA

10.93

-5.21

-5.96

PFPVPQQQF

11.83

-2.24

-2.99

PLPDPPQHN

11.99

-1.52

-2.27

P40453

KVPEPPSWK

14.48

-2.75

-3.50

PPDLPIRLR

16.16

-7.71

-8.46

CPRCGPTAS

17.26

-2.64

-3.39

P40343

SPQPQPIHS

16.30

-1.75

-2.50

SDPPYPKEE

16.74

0.95

0.20

APSDPPYPK

18.36

-1.28

-2.03

Q03497

FPSKNPLKN

11.69

-5.72

-6.47

VKPSKPEAK

12.90

0.09

-0.66

PPIPPTKSK

13.29

-3.46

-4.21

P53238

IPPAPTHYN

16.26

-3.55

-4.30

PIPPAPTHY

17.22

-1.49

-2.24

P40041

KIPLSPPSS

16.06

-3.84

-4.59

IPLSPPSSS

17.61

-3.13

-3.88

 


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