ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: HSE1_1OEB-15.PDB
Scoring matrix: HSE1_1OEB-15_mat
Uniprot code: P38753
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 19.26
Foldx random average score for Saccharomyces cerevisiae: 14.239

Available information for P38753 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 49
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2079
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5100
 Total fragments: 2188715
Proteins after random average filtering: 5100
 Total fragments: 899202
Proteins after disorder filtering: 2727
 Total fragments: 29155
Proteins after pattern filtering: 1115
 Total fragments: 3652
Proteins after MINT filtering: 16
 Total fragments: 148


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

19.26

-1.39

0.00

Best peptides

YWRRRRKNR

0.00

-7.53

-6.14

         
Interactors      
Q06604

PLLPTRPNK

10.38

-6.54

-5.15

LLPTRPNKA

11.38

-5.84

-4.45

LPTRPNKAE

11.60

-7.28

-5.89

Q06108

PPPQPRRLS

11.59

-7.73

-6.34

LPGVSPSCL

12.68

-6.23

-4.84

NMPIPKKLP

12.77

-8.14

-6.75

P40073

YPQQQPSHT

11.69

-5.78

-4.39

P25604

LPPKPNTQL

12.67

-8.07

-6.68

KPKSPHLKP

12.88

-7.82

-6.43

PKPKSPHLK

12.88

-5.96

-4.57

P40325

RPHQRPSTM

9.38

-8.88

-7.49

RPPRPAANL

9.87

-7.90

-6.51

HQSRPHQRP

10.23

-8.32

-6.93

O13527

MIPYTPYQM

11.23

-5.88

-4.49

VPLNPKGKK

11.67

-6.69

-5.30

HPSMIPYTP

11.68

-7.00

-5.61

P48524

RKPLLRPQR

7.27

-9.99

-8.60

PPKRKPLLR

8.85

-9.56

-8.17

FPPKRKPLL

10.10

-7.78

-6.39

Q06412

SPMVSPSSQ

12.93

-5.37

-3.98

PKLPPLNTR

13.15

-5.71

-4.32

KERRPPPPP

13.57

-7.90

-6.51

P40453

PDLPIRLRK

11.03

-6.23

-4.84

PPDLPIRLR

11.99

-8.47

-7.08

PPPVSMPTT

12.11

-6.30

-4.91

P36037

KPPLKLPIN

11.25

-8.12

-6.73

PPLKLPINV

12.46

-6.61

-5.22

P36041

PPNFPQRMM

11.38

-7.21

-5.82

NSPMPIPSI

11.51

-5.64

-4.25

RPVIPRGPS

11.59

-8.78

-7.39

Q04439

NIPTPPQNR

9.91

-7.16

-5.77

PPPPGMQNK

12.79

-6.65

-5.26

KPAPPPPGM

14.13

-6.87

-5.48

P53901

PPIPTRDDM

11.94

-6.30

-4.91

PPLPPIPTR

13.20

-6.08

-4.69

MAMRPIPPL

13.46

-8.03

-6.64

Q12446

RPLPQLPNR

9.29

-7.04

-5.65

PQLPNRNNR

11.16

-5.39

-4.00

PPPPPRASR

11.18

-8.57

-7.18

Q03497

HKPKVKPSK

9.61

-6.21

-4.82

HAPTTPNRT

11.88

-4.63

-3.24

KPKVKPSKP

11.95

-8.23

-6.84

P53238

QKPAGRPIP

13.95

-6.38

-4.99

PPAPTHYNN

14.19

-5.43

-4.04

 


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