ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: HSE1_1OEB-14.PDB
Scoring matrix: HSE1_1OEB-14_mat
Uniprot code: P38753
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 21.52
Foldx random average score for Saccharomyces cerevisiae: 17.550

Available information for P38753 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 49
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2079
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5100
 Total fragments: 2188715
Proteins after random average filtering: 5100
 Total fragments: 954099
Proteins after disorder filtering: 2976
 Total fragments: 38105
Proteins after pattern filtering: 1228
 Total fragments: 4279
Proteins after MINT filtering: 18
 Total fragments: 164


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

21.52

-3.06

0.00

Best peptides

RWPRKRKRR

0.00

-10.18

-7.12

         
Interactors      
Q06604

PLLPTRPNK

11.67

-9.30

-6.24

KGPRMPSRG

12.60

-7.49

-4.43

EEKPLLPTR

13.36

-4.74

-1.68

Q06108

PPPQPRRLS

12.42

-9.28

-6.22

TDPPPQPRR

13.77

-5.92

-2.86

QPATPGSTR

14.32

-6.89

-3.83

P25604

PKPKSPHLK

14.00

-7.34

-4.28

LPPKPKSPH

14.46

-7.82

-4.76

LPPKPNTQL

15.09

-6.92

-3.86

P40325

RPPRPAANL

12.78

-10.05

-6.99

SLPWTYPPR

13.66

-7.42

-4.36

RPHQRPSTM

13.80

-7.20

-4.14

O13527

VPLNPKGKK

12.07

-7.57

-4.51

MSPMYFPPG

14.63

-7.91

-4.85

MIPYTPYQM

15.23

-5.81

-2.75

P48524

RKPLLRPQR

5.67

-11.90

-8.84

PPKRKPLLR

7.20

-10.87

-7.81

KPLLRPQRS

12.67

-9.08

-6.02

Q06412

SPNSPKSPR

13.52

-7.24

-4.18

PKLPPLNTR

14.71

-6.67

-3.61

SPKSPRDSS

15.13

-7.48

-4.42

Q66RC5

PDNPGRLLS

14.39

-6.48

-3.42

PLIPDNPGR

15.29

-6.31

-3.25

P36037

KPPLKLPIN

10.47

-8.66

-5.60

PPLKLPINV

16.24

-7.30

-4.24

P36041

RPVIPRGPS

10.92

-10.73

-7.67

TDLRPVIPR

12.38

-8.74

-5.68

GVPPNFPQR

13.94

-6.36

-3.30

Q04439

NIPTPPQNR

12.35

-8.26

-5.20

PPPPGMQNK

14.14

-9.15

-6.09

PPPSSKPKE

15.08

-6.12

-3.06

P53901

PPIPTRDDM

14.27

-7.96

-4.90

PPLPPIPTR

14.73

-6.37

-3.31

MAMRPIPPL

15.65

-9.15

-6.09

Q12446

RPLPQLPNR

10.36

-9.07

-6.01

PPPPPRASR

10.74

-11.78

-8.72

PQLPNRNNR

11.10

-9.43

-6.37

P40453

PDLPIRLRK

10.19

-8.02

-4.96

PPDLPIRLR

10.79

-9.26

-6.20

WKPPDLPIR

12.66

-6.84

-3.78

P40343

PSPQPQPIH

17.29

-5.75

-2.69

APSDPPYPK

17.48

-5.36

-2.30

Q03497

HKPKVKPSK

12.65

-7.53

-4.47

SFPSKNPLK

13.03

-5.48

-2.42

VKPSKPEAK

14.61

-4.39

-1.33

P53238

PPAPTHYNN

15.47

-7.69

-4.63

PAGRPIPPA

15.69

-9.02

-5.96

P40041

KIPLSPPSS

15.39

-7.38

-4.32

 


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