ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: HSE1_1OEB-12.PDB
Scoring matrix: HSE1_1OEB-12_mat
Uniprot code: P38753
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 12.8
Foldx random average score for Saccharomyces cerevisiae: 10.533

Available information for P38753 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 49
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2079
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5100
 Total fragments: 2193815
Proteins after random average filtering: 5100
 Total fragments: 900533
Proteins after disorder filtering: 3066
 Total fragments: 48201
Proteins after pattern filtering: 1488
 Total fragments: 9313
Proteins after MINT filtering: 20
 Total fragments: 413


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

12.80

-1.94

0.00

Best peptides

YRVKRKRK

0.00

-6.55

-4.61

         
Interactors      
Q07660

SAFKPIGP

7.34

-5.18

-3.24

Q06604

PSPPAKRI

4.04

-6.11

-4.17

PRMPSRGR

7.38

-6.48

-4.54

PTRPNKAE

7.45

-4.67

-2.73

Q06108

PPPQPRRL

6.22

-5.69

-3.75

DPPPQPRR

6.66

-6.04

-4.10

TDPPPQPR

7.51

-3.74

-1.80

P40073

DGYPQQQP

7.87

-3.96

-2.02

GYPQQQPS

8.33

-3.73

-1.79

PQQQPSHT

9.55

-2.16

-0.22

P25604

PKPKSPHL

6.65

-3.80

-1.86

LPPKPKSP

7.26

-4.78

-2.84

HLKPPLPP

7.54

-5.42

-3.48

P40325

QSRPHQRP

4.69

-5.17

-3.23

QPPRPPRP

6.12

-6.56

-4.62

QPRPPPRP

6.49

-5.39

-3.45

O13527

QSQFPQYP

6.93

-3.05

-1.11

SQFPQYPS

7.67

-5.28

-3.34

IHPRGIPG

8.08

-3.62

-1.68

P48524

KRKPLLRP

4.30

-6.71

-4.77

PKRKPLLR

5.99

-5.29

-3.35

FPPKRKPL

6.43

-5.11

-3.17

Q06412

NSPKSPRD

5.53

-5.07

-3.13

ERRPPPPP

7.18

-4.59

-2.65

KERRPPPP

7.27

-5.04

-3.10

Q66RC5

SNPSPLIP

9.47

-3.82

-1.88

PDNPGRLL

10.46

-4.40

-2.46

P36037

GKPPLKLP

6.22

-4.52

-2.58

KPPLKLPI

9.03

-3.37

-1.43

PLKLPINV

9.17

-4.23

-2.29

P36041

LRPVIPRG

6.39

-3.29

-1.35

PGFFPMHP

6.54

-5.82

-3.88

GFFPMHPN

6.99

-6.02

-4.08

Q04439

PTPPQNRD

7.41

-4.30

-2.36

SKPKEPMF

7.65

-3.52

-1.58

SKKPAPPP

7.86

-4.10

-2.16

P53901

MAMRPIPP

7.54

-6.20

-4.26

YNQPPLPP

7.85

-4.44

-2.50

NSPKLPPL

8.12

-2.85

-0.91

Q12446

PPPPPHRH

5.61

-6.43

-4.49

PPPPPMRT

5.94

-6.45

-4.51

PPPPPRRG

6.15

-7.64

-5.70

P40453

PEPPSWKP

5.75

-5.68

-3.74

LRKRPPPP

6.78

-4.33

-2.39

TKVPEPPS

6.83

-4.80

-2.86

P40343

PQPQPIHS

7.64

-4.61

-2.67

PSPQPQPI

7.76

-3.23

-1.29

SDPPYPKE

8.62

-3.86

-1.92

Q03497

HKPKVKPS

5.61

-4.85

-2.91

GKFIPSRP

5.92

-3.98

-2.04

SRPAPKPP

6.07

-3.95

-2.01

P53238

QKPAGRPI

8.10

-4.28

-2.34

GRPIPPAP

8.76

-2.56

-0.62

AGRPIPPA

9.12

-4.27

-2.33

P40041

KIPLSPPS

9.02

-2.25

-0.31

GRTLPPVP

9.64

-2.19

-0.25

 


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