ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: HSE1_1OEB-1.PDB
Scoring matrix: HSE1_1OEB-1_mat
Uniprot code: P38753
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 29.8
Foldx random average score for Saccharomyces cerevisiae: 25.287

Available information for P38753 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 49
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2079
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5100
 Total fragments: 2183615
Proteins after random average filtering: 5100
 Total fragments: 924129
Proteins after disorder filtering: 3008
 Total fragments: 45335
Proteins after pattern filtering: 1445
 Total fragments: 8477
Proteins after MINT filtering: 19
 Total fragments: 321


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

29.80

-3.67

0.00

Best peptides

WRKRRFRRPY

0.00

-13.16

-9.49

         
Interactors      
Q06604

MKNKPKPTPP

12.36

-12.00

-8.33

KGPRMPSRGR

15.56

-7.56

-3.89

LLPTRPNKAE

17.84

-7.66

-3.99

Q06108

LKSTDPPPQP

16.09

-9.47

-5.80

PRSPYYINMP

18.54

-10.85

-7.18

CKSPYSPYTG

20.09

-6.21

-2.54

P40073

QFDGYPQQQP

24.10

-7.96

-4.29

DGYPQQQPSH

24.52

-2.52

1.15

GYPQQQPSHT

24.88

-6.71

-3.04

P25604

HLKPPLPPPP

13.43

-12.05

-8.38

LKPPLPPPPP

14.91

-9.83

-6.16

PKPKSPHLKP

16.12

-8.24

-4.57

P40325

HQSRPHQRPS

15.77

-8.99

-5.32

PRPQQNPSLP

16.25

-9.18

-5.51

SQPRPPPRPQ

17.55

-7.43

-3.76

O13527

GKKLRAPGQP

16.35

-7.48

-3.81

FYGHPSMIPY

18.08

-8.84

-5.17

DLPPESPTEF

19.61

-5.55

-1.88

P48524

KRKPLLRPQR

10.13

-13.24

-9.57

PLLRPQRSDF

13.88

-10.67

-7.00

PKRKPLLRPQ

14.50

-9.47

-5.80

Q06412

VKERRPPPPP

11.13

-11.62

-7.95

RRPPPPPPLL

13.94

-12.40

-8.73

KERRPPPPPP

15.61

-10.84

-7.17

Q66RC5

PLIPDNPGRL

21.55

-5.58

-1.91

P36037

DGKPPLKLPI

21.96

-6.70

-3.03

GKPPLKLPIN

22.04

-7.00

-3.33

P36041

LRPVIPRGPS

13.42

-12.42

-8.75

QRMMPPPPGL

16.52

-6.47

-2.80

PLPQGFPIPP

16.61

-8.63

-4.96

Q04439

RHSKKPAPPP

14.45

-12.01

-8.34

KKPAPPPPGM

16.41

-7.49

-3.82

SRHSKKPAPP

16.62

-11.39

-7.72

P53901

MRPIPPLPTE

16.13

-9.36

-5.69

AMRPIPPLPT

20.08

-7.47

-3.80

PKLPPLPTTS

20.25

-4.80

-1.13

Q12446

RRGPAPPPPP

12.15

-11.76

-8.09

RLPAPPPPPR

13.45

-9.68

-6.01

TKHKAPPPPP

13.56

-9.43

-5.76

P40453

LRKRPPPPPP

9.25

-14.14

-10.47

RLRKRPPPPP

9.31

-14.60

-10.93

IRLRKRPPPP

10.02

-11.29

-7.62

P40343

ELAPSDPPYP

20.13

-5.79

-2.12

LAPSDPPYPK

22.60

-8.72

-5.05

QQPSPQPQPI

23.56

-3.57

0.10

Q03497

HKPKVKPSKP

12.61

-11.21

-7.54

HKQHKPKVKP

14.37

-12.04

-8.37

KKSFPSKNPL

14.79

-7.98

-4.31

P53238

GRPIPPAPTH

18.22

-6.66

-2.99

QKPAGRPIPP

18.42

-7.87

-4.20

AGRPIPPAPT

21.83

-6.77

-3.10

P40041

PLSPPSSSNM

21.32

-6.26

-2.59

PNGRTLPPVP

21.94

-9.42

-5.75

 


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