ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: HSE1_1GCQ-9.PDB
Scoring matrix: HSE1_1GCQ-9_mat
Uniprot code: P38753
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 17.89
Foldx random average score for Saccharomyces cerevisiae: 13.895

Available information for P38753 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 49
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2079
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5100
 Total fragments: 2193815
Proteins after random average filtering: 5100
 Total fragments: 937306
Proteins after disorder filtering: 3092
 Total fragments: 44221
Proteins after pattern filtering: 1504
 Total fragments: 8463
Proteins after MINT filtering: 20
 Total fragments: 355


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

17.89

-1.74

0.00

Best peptides

YPPRPNRY

0.00

-11.40

-9.66

         
Interactors      
Q07660

SAFKPIGP

13.39

-7.22

-5.48

Q06604

KPLLPTRP

4.50

-11.96

-10.22

LPTRPNKA

5.74

-10.80

-9.06

PPPLPTRR

6.88

-12.15

-10.41

Q06108

PPPQPRRL

6.26

-11.31

-9.57

DPPPQPRR

9.31

-9.01

-7.27

TDPRSPYY

9.87

-7.48

-5.74

P40073

YPQQQPSH

11.21

-6.37

-4.63

PQQQPSHT

13.70

-5.51

-3.77

P25604

APSLPPKP

6.22

-10.60

-8.86

TPPLPPKP

6.71

-10.33

-8.59

KPPLPPPP

8.16

-10.39

-8.65

P40325

QPPRPPRP

4.33

-13.18

-11.44

QPRPPPRP

7.27

-10.40

-8.66

RPPRPAAN

7.85

-11.30

-9.56

O13527

IPYTPYQM

9.26

-6.89

-5.15

LPDLPPES

10.35

-8.02

-6.28

NVPLNPKG

10.94

-7.32

-5.58

P48524

KRKPLLRP

7.36

-8.24

-6.50

PLLRPQRS

8.00

-10.10

-8.36

KPLLRPQR

8.87

-9.37

-7.63

Q06412

FFTKPPPP

9.04

-9.31

-7.57

KERRPPPP

9.07

-11.64

-9.90

NSPKSPRD

9.16

-7.32

-5.58

Q66RC5

IPDNPGRL

6.86

-8.14

-6.40

SPLIPDNP

12.26

-6.86

-5.12

SNPSPLIP

13.14

-6.22

-4.48

P36037

KPPLKLPI

9.59

-8.27

-6.53

PPLKLPIN

10.06

-7.63

-5.89

PLKLPINV

12.77

-7.78

-6.04

P36041

PPNFPQRM

7.79

-8.47

-6.73

FFPMHPNF

8.11

-9.12

-7.38

FPMHPNFP

8.59

-8.93

-7.19

Q04439

KPKEPMFE

8.91

-7.25

-5.51

PPSSKPKE

10.26

-7.55

-5.81

PTPPQNRD

10.34

-6.52

-4.78

P53901

LPPIPTRD

5.13

-10.67

-8.93

MRPIPPLP

7.66

-11.83

-10.09

QPPLPPIP

8.55

-10.26

-8.52

Q12446

LPQLPNRN

3.31

-10.97

-9.23

LPPLPNQF

6.44

-9.87

-8.13

KHSLPPLP

7.07

-9.46

-7.72

P40453

PPDLPIRL

5.74

-10.89

-9.15

PPPLPPKI

6.21

-10.18

-8.44

LRKRPPPP

9.03

-11.58

-9.84

P40343

SDPPYPKE

11.21

-6.57

-4.83

APSDPPYP

11.61

-8.10

-6.36

QPSPQPQP

11.98

-6.39

-4.65

Q03497

GKFIPSRP

6.42

-10.79

-9.05

PKVKPSKP

7.08

-9.25

-7.51

APTTPNRT

7.47

-9.40

-7.66

P53238

IPPAPTHY

10.19

-7.12

-5.38

KPAGRPIP

11.37

-8.07

-6.33

GRPIPPAP

11.48

-7.69

-5.95

P40041

GRTLPPVP

11.13

-9.14

-7.40

KIPLSPPS

12.04

-6.57

-4.83

IPLSPPSS

13.27

-5.86

-4.12

 


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