ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: HSE1_1GCQ-7.PDB
Scoring matrix: HSE1_1GCQ-7_mat
Uniprot code: P38753
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAA
Foldx wt ligand score: 12.06
Foldx random average score for Saccharomyces cerevisiae: 10.899

Available information for P38753 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 49
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2079
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5100
 Total fragments: 2193815
Proteins after random average filtering: 5100
 Total fragments: 1037916
Proteins after disorder filtering: 3316
 Total fragments: 74785
Proteins after pattern filtering: 1591
 Total fragments: 10003
Proteins after MINT filtering: 19
 Total fragments: 364


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AGAAAAAA

12.06

-1.92

0.00

Best peptides

KHPVNPWM

0.00

-2.53

-0.61

         
Interactors      
Q06604

EKPLLPTR

7.11

-5.81

-3.89

KPAPPVSR

7.12

-4.60

-2.68

SPPPLPTR

7.32

-3.73

-1.81

Q06108

KSPYSPYT

4.70

-4.37

-2.45

TDPRSPYY

6.39

-7.41

-5.49

DPPPQPRR

6.96

-7.62

-5.70

P40073

YPQQQPSH

9.23

-4.08

-2.16

P25604

PKPKSPHL

7.23

-6.04

-4.12

PPPPQPAS

7.39

-4.27

-2.35

SLPPKPNT

7.66

-3.48

-1.56

P40325

RPPPRPQQ

7.79

-5.98

-4.06

PHQRPSTM

7.80

-7.53

-5.61

PRPPRPAA

7.96

-4.62

-2.70

O13527

AVPENPHH

6.01

-3.52

-1.60

QMSPMYFP

6.12

-6.08

-4.16

PLNPKGKK

8.09

-5.98

-4.06

P48524

KRKPLLRP

7.71

-6.53

-4.61

KPLLRPQR

7.96

-8.46

-6.54

RKPLLRPQ

8.84

-5.27

-3.35

Q06412

PPPPLLYS

6.00

-5.59

-3.67

KPPPPLST

7.42

-4.52

-2.60

PPPPLSTS

7.81

-4.43

-2.51

Q66RC5

IPDNPGRL

8.06

-5.39

-3.47

NPSPLIPD

10.18

-3.14

-1.22

P36037

KPPLKLPI

8.38

-6.68

-4.76

PLKLPINV

8.63

-6.59

-4.67

GKPPLKLP

9.82

-4.27

-2.35

P36041

PPPPPGFF

5.21

-6.25

-4.33

MMPPPPGL

6.60

-6.46

-4.54

PPLPQGFP

6.61

-6.47

-4.55

Q04439

KPKEPMFE

4.96

-6.63

-4.71

IPTPPQNR

7.66

-5.43

-3.51

PPPPPSSK

7.85

-4.91

-2.99

P53901

KLPPLPTT

5.89

-4.35

-2.43

PIPPLPTE

8.10

-4.02

-2.10

IPPLPTES

8.23

-4.24

-2.32

Q12446

PPPPPAFL

5.60

-6.47

-4.55

PPLPNQFA

5.94

-5.46

-3.54

APPPPPHR

6.74

-5.33

-3.41

P40453

KVPEPPSW

6.12

-5.56

-3.64

VPEPPSWK

6.25

-6.00

-4.08

PPPPPVSM

7.04

-5.27

-3.35

P40343

SPQPQPIH

8.45

-4.28

-2.36

DPPYPKEE

9.03

-3.33

-1.41

APSDPPYP

9.17

-5.55

-3.63

Q03497

KPKVKPSK

5.62

-5.58

-3.66

PKPPSSAS

7.47

-3.88

-1.96

KSFPSKNP

7.69

-3.42

-1.50

P53238

IPPAPTHY

6.52

-2.60

-0.68

PIPPAPTH

9.44

-3.55

-1.63

KPAGRPIP

9.55

-4.75

-2.83

P40041

PLSPPSSS

8.60

-4.48

-2.56

KIPLSPPS

8.73

-6.07

-4.15

 


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