ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: HSE1_1GCQ-5.PDB
Scoring matrix: HSE1_1GCQ-5_mat
Uniprot code: P38753
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 22.89
Foldx random average score for Saccharomyces cerevisiae: 22.429

Available information for P38753 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 49
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2079
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5100
 Total fragments: 2183615
Proteins after random average filtering: 5100
 Total fragments: 1093358
Proteins after disorder filtering: 3167
 Total fragments: 72145
Proteins after pattern filtering: 1560
 Total fragments: 11797
Proteins after MINT filtering: 19
 Total fragments: 400


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

22.89

7.26

0.00

Best peptides

MRHWPFRDHW

0.00

-1.17

-8.43

         
Interactors      
Q06604

MKNKPKPTPP

15.07

-3.90

-11.16

KGPRMPSRGR

16.34

-6.57

-13.83

PKPTPPSPPA

17.91

-3.57

-10.83

Q06108

PRSPYYINMP

12.38

-4.82

-12.08

LKSTDPPPQP

14.90

-4.41

-11.67

GGISKQPATP

17.93

-1.30

-8.56

P40073

DGYPQQQPSH

20.72

0.52

-6.74

QFDGYPQQQP

20.85

-1.47

-8.73

GYPQQQPSHT

21.95

-3.77

-11.03

P25604

PHLKPPLPPP

14.87

-7.43

-14.69

LKPPLPPPPP

15.40

-4.03

-11.29

PKPKSPHLKP

17.10

-5.82

-13.08

P40325

SRPHQRPSTM

11.27

-4.19

-11.45

PRPQQNPSLP

11.45

-4.98

-12.24

PRPPPRPQQN

13.79

-6.49

-13.75

O13527

PRGIPGYALH

14.09

-6.34

-13.60

MSPMYFPPGP

14.24

-4.37

-11.63

ESPTEFPDPF

15.25

-2.80

-10.06

P48524

PLLRPQRSDF

14.04

-5.91

-13.17

KRKPLLRPQR

15.41

-3.59

-10.85

RKPLLRPQRS

17.63

-1.59

-8.85

Q06412

RRPPPPPPLL

12.83

-4.22

-11.48

ERRPPPPPPL

13.54

-4.72

-11.98

VKERRPPPPP

14.11

-6.64

-13.90

Q66RC5

SISNPSPLIP

19.45

-2.59

-9.85

ISNPSPLIPD

20.32

-4.98

-12.24

PSPLIPDNPG

20.69

-1.81

-9.07

P36037

EDGKPPLKLP

20.09

0.81

-6.45

GKPPLKLPIN

21.59

-5.15

-12.41

DGKPPLKLPI

22.03

-1.15

-8.41

P36041

LRPVIPRGPS

10.89

-2.25

-9.51

QRMMPPPPGL

12.54

-8.81

-16.07

MGVPPNFPQR

14.23

-5.40

-12.66

Q04439

HSKKPAPPPP

15.01

-5.61

-12.87

SRHSKKPAPP

15.57

-3.61

-10.87

ARPSPPTAAT

15.66

-3.01

-10.27

P53901

MRPIPPLPTE

9.74

-5.69

-12.95

HNYNQPPLPP

16.66

-3.72

-10.98

NSPKLPPLPT

17.71

-2.51

-9.77

Q12446

NRPVPPPPPM

10.80

-7.16

-14.42

PRRGPAPPPP

11.11

-8.77

-16.03

RRGPAPPPPP

11.41

-2.43

-9.69

P40453

LRKRPPPPPP

8.15

-6.58

-13.84

IRLRKRPPPP

9.40

-4.56

-11.82

KRPPPPPPVS

13.63

-5.54

-12.80

P40343

HVELAPSDPP

16.93

-2.02

-9.28

LAPSDPPYPK

17.01

-3.30

-10.56

QQPSPQPQPI

18.26

-2.88

-10.14

Q03497

HKQHKPKVKP

14.90

-7.39

-14.65

GKFIPSRPAP

15.38

-2.76

-10.02

VKKSFPSKNP

16.44

-4.25

-11.51

P53238

GRPIPPAPTH

13.94

-3.82

-11.08

QKPAGRPIPP

17.22

-3.83

-11.09

AGRPIPPAPT

17.68

-3.68

-10.94

P40041

PLSPPSSSNM

19.09

-5.94

-13.20

KIPLSPPSSS

20.11

-3.30

-10.56

PNGRTLPPVP

21.94

-2.79

-10.05

 


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