ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: HSE1_1GCQ-29.PDB
Scoring matrix: HSE1_1GCQ-29_mat
Uniprot code: P38753
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 21.33
Foldx random average score for Saccharomyces cerevisiae: 14.999

Available information for P38753 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 49
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2079
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5100
 Total fragments: 2183615
Proteins after random average filtering: 5099
 Total fragments: 978461
Proteins after disorder filtering: 2858
 Total fragments: 39183
Proteins after pattern filtering: 1494
 Total fragments: 10020
Proteins after MINT filtering: 19
 Total fragments: 414


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

21.33

-1.71

0.00

Best peptides

DLPPRHKRMK

0.00

-10.76

-9.05

         
Interactors      
Q06604

EKPLLPTRPN

5.10

-15.57

-13.86

SPPPLPTRRD

6.08

-12.94

-11.23

LLPTRPNKAE

7.10

-10.95

-9.24

Q06108

DPPPQPRRLS

6.82

-13.24

-11.53

KTDPRSPYYI

9.97

-4.63

-2.92

INMPIPKKLP

10.64

-10.76

-9.05

P40073

GYPQQQPSHT

13.63

-7.60

-5.89

QFDGYPQQQP

14.59

-6.46

-4.75

DGYPQQQPSH

14.87

-5.17

-3.46

P25604

PLPPKPKSPH

7.07

-10.78

-9.07

NTPPLPPKPK

7.96

-10.68

-8.97

QAPSLPPKPN

8.72

-11.21

-9.50

P40325

SQPPRPPRPA

3.34

-13.90

-12.19

SQPRPPPRPQ

8.42

-12.38

-10.67

RPPPRPQQNP

8.77

-9.66

-7.95

O13527

HPRGIPGYAL

9.14

-10.32

-8.61

GHPSMIPYTP

10.19

-9.38

-7.67

LNVPLNPKGK

11.13

-7.79

-6.08

P48524

KPLLRPQRSD

6.56

-11.89

-10.18

FPPKRKPLLR

7.44

-13.74

-12.03

RKPLLRPQRS

8.95

-10.64

-8.93

Q06412

VKERRPPPPP

9.18

-11.17

-9.46

YVKERRPPPP

10.27

-10.66

-8.95

EFFTKPPPPL

10.54

-9.15

-7.44

Q66RC5

LIPDNPGRLL

10.01

-10.62

-8.91

PSPLIPDNPG

10.15

-10.32

-8.61

ISNPSPLIPD

14.59

-6.40

-4.69

P36037

PPLKLPINVS

10.17

-9.83

-8.12

GKPPLKLPIN

10.32

-10.27

-8.56

KPPLKLPINV

10.93

-9.73

-8.02

P36041

DLRPVIPRGP

8.18

-10.33

-8.62

VPPNFPQRMM

8.34

-12.01

-10.30

PTDLRPVIPR

9.26

-9.52

-7.81

Q04439

SKPKEPMFEA

11.28

-8.94

-7.23

QSNARPSPPT

11.32

-9.24

-7.53

PPPPPSSKPK

11.54

-9.17

-7.46

P53901

PLPPIPTRDD

5.92

-13.10

-11.39

NQPPLPPIPT

7.69

-11.49

-9.78

AMRPIPPLPT

7.86

-11.92

-10.21

Q12446

PPPPRASRPT

5.56

-13.55

-11.84

PLPQLPNRNN

6.42

-13.66

-11.95

SLPPLPNQFA

7.72

-10.61

-8.90

P40453

KPPDLPIRLR

6.10

-14.86

-13.15

RLRKRPPPPP

7.42

-11.84

-10.13

PDLPIRLRKR

8.22

-12.35

-10.64

P40343

LAPSDPPYPK

10.88

-9.77

-8.06

SPQPQPIHSV

12.87

-8.43

-6.72

QQPSPQPQPI

13.15

-7.46

-5.75

Q03497

NGKFIPSRPA

6.85

-12.42

-10.71

KPKVKPSKPE

8.81

-10.60

-8.89

PLPPIPPTKS

9.45

-10.85

-9.14

P53238

AGRPIPPAPT

10.91

-9.82

-8.11

KPAGRPIPPA

11.42

-9.58

-7.87

PIPPAPTHYN

11.87

-8.21

-6.50

P40041

KIPLSPPSSS

14.12

-5.04

-3.33

IPLSPPSSSN

14.85

-5.31

-3.60

 


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