ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: HSE1_1GCQ-27.PDB
Scoring matrix: HSE1_1GCQ-27_mat
Uniprot code: P38753
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAAA
Foldx wt ligand score: 16.49
Foldx random average score for Saccharomyces cerevisiae: 15.905

Available information for P38753 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 49
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2079
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5100
 Total fragments: 2188715
Proteins after random average filtering: 5100
 Total fragments: 1081213
Proteins after disorder filtering: 3245
 Total fragments: 87683
Proteins after pattern filtering: 1580
 Total fragments: 10783
Proteins after MINT filtering: 18
 Total fragments: 372


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AGAAAAAAA

16.49

-2.26

0.00

Best peptides

RHWHWDFRR

0.00

-3.38

-1.12

         
Interactors      
Q06604

KGPRMPSRG

7.00

-5.26

-3.00

FEKGPRMPS

11.27

-6.00

-3.74

LPTRPNKAE

11.56

-5.38

-3.12

Q06108

RTPCKSPYS

9.85

-6.13

-3.87

PCKSPYSPY

11.50

-4.92

-2.66

TDPRSPYYI

12.02

-3.36

-1.10

P40073

YPQQQPSHT

11.46

-2.05

0.21

FDGYPQQQP

13.36

-4.46

-2.20

P25604

KSPHLKPPL

8.63

-5.49

-3.23

LPPKPKSPH

11.32

-5.33

-3.07

KPKSPHLKP

11.94

-5.70

-3.44

P40325

RPPRPAANL

9.33

-5.78

-3.52

QPPRPPRPA

9.61

-5.95

-3.69

HQSRPHQRP

9.63

-7.08

-4.82

O13527

SKIHPRGIP

8.39

-4.32

-2.06

FYGHPSMIP

8.44

-7.08

-4.82

YQMSPMYFP

8.93

-5.33

-3.07

P48524

PKRKPLLRP

11.46

-5.88

-3.62

FPPKRKPLL

11.87

-6.61

-4.35

PLLRPQRSD

12.64

-3.38

-1.12

Q06412

FFTKPPPPL

9.03

-4.52

-2.26

VKERRPPPP

9.42

-5.70

-3.44

KERRPPPPP

9.68

-4.38

-2.12

Q66RC5

LIPDNPGRL

12.22

-3.54

-1.28

IPDNPGRLL

12.46

-4.97

-2.71

P36041

FPMHPNFPN

5.95

-6.69

-4.43

FPNGPMPPL

9.56

-6.01

-3.75

PGFFPMHPN

9.69

-4.22

-1.96

Q04439

KKPAPPPPG

8.52

-6.79

-4.53

RHSKKPAPP

9.17

-7.95

-5.69

SNARPSPPT

9.97

-3.62

-1.36

P53901

MAMRPIPPL

8.78

-5.83

-3.57

YNQPPLPPI

11.40

-5.10

-2.84

PNSHPHPSG

11.53

-3.08

-0.82

Q12446

RNNRPVPPP

6.62

-8.63

-6.37

RGPAPPPPP

6.93

-8.64

-6.38

RLPAPPPPP

7.52

-8.28

-6.02

P40453

LRKRPPPPP

7.48

-7.46

-5.20

RKRPPPPPP

9.36

-7.00

-4.74

RLRKRPPPP

9.60

-7.09

-4.83

P40343

LAPSDPPYP

12.11

-4.94

-2.68

APSDPPYPK

12.71

-2.91

-0.65

PSPQPQPIH

12.98

-1.87

0.39

Q03497

NGKFIPSRP

9.77

-3.61

-1.35

FIPSRPAPK

9.78

-5.81

-3.55

SRPAPKPPS

9.97

-6.26

-4.00

P53238

IPPAPTHYN

10.70

-4.77

-2.51

PAGRPIPPA

11.08

-5.09

-2.83

QKPAGRPIP

12.35

-4.67

-2.41

P40041

IPLSPPSSS

10.84

-3.57

-1.31

 


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