ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: HSE1_1GCQ-26.PDB
Scoring matrix: HSE1_1GCQ-26_mat
Uniprot code: P38753
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 15.57
Foldx random average score for Saccharomyces cerevisiae: 12.744

Available information for P38753 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 49
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2079
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5100
 Total fragments: 2188715
Proteins after random average filtering: 5100
 Total fragments: 986017
Proteins after disorder filtering: 3065
 Total fragments: 55619
Proteins after pattern filtering: 1582
 Total fragments: 13578
Proteins after MINT filtering: 20
 Total fragments: 544


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

15.57

-1.71

0.00

Best peptides

DDMPRRPPR

0.00

-10.75

-9.04

         
Interactors      
Q07660

PSAFKPIGP

11.29

-3.03

-1.32

Q06604

SSPPPLPTR

2.65

-10.40

-8.70

EEKPLLPTR

3.50

-10.06

-8.36

EKGPRMPSR

5.00

-9.58

-7.88

Q06108

TDPPPQPRR

4.81

-9.67

-7.96

DPPPQPRRL

7.37

-5.87

-4.17

STDPPPQPR

7.81

-7.15

-5.45

P40073

GYPQQQPSH

9.34

-6.20

-4.50

DGYPQQQPS

11.33

-4.56

-2.85

P25604

DQAPSLPPK

5.51

-8.42

-6.71

HLKPPLPPP

7.00

-8.59

-6.88

PLPPPPPPQ

7.58

-7.93

-6.22

P40325

QSQPPRPPR

3.00

-10.09

-8.38

SSQPRPPPR

4.24

-7.51

-5.80

PRPPPRPQQ

5.19

-11.94

-10.23

O13527

YGHPSMIPY

7.20

-6.15

-4.45

IHPRGIPGY

7.25

-7.50

-5.79

SMIPYTPYQ

9.09

-5.97

-4.26

P48524

RKPLLRPQR

3.79

-10.52

-8.81

KRKPLLRPQ

6.06

-7.67

-5.96

PPKRKPLLR

6.10

-6.19

-4.49

Q06412

PKLPPLNTR

6.92

-8.24

-6.54

RRPPPPPPL

7.27

-8.43

-6.72

PPPPLSTSR

7.48

-6.46

-4.75

Q66RC5

PLIPDNPGR

6.85

-7.70

-6.00

PDNPGRLLS

8.80

-8.93

-7.22

NPSPLIPDN

8.96

-6.83

-5.13

P36037

KPPLKLPIN

7.10

-8.43

-6.72

GKPPLKLPI

7.83

-8.62

-6.91

DGKPPLKLP

9.91

-6.32

-4.62

P36041

GVPPNFPQR

6.69

-8.30

-6.60

MPPPPPPGF

6.73

-7.41

-5.71

PPPPGLIAH

6.81

-5.72

-4.01

Q04439

SSKPKEPMF

6.79

-6.34

-4.63

PSPPTAATR

7.69

-7.08

-5.38

PPPPGMQNK

8.19

-7.13

-5.42

P53901

PPLPPIPTR

5.21

-10.40

-8.70

MAMRPIPPL

6.35

-8.06

-6.36

YNQPPLPPI

6.70

-7.59

-5.88

Q12446

PPPPPRASR

3.74

-11.48

-9.78

PAPPPPPRR

4.68

-8.92

-7.21

PAPPPPPHR

5.00

-8.80

-7.10

P40453

WKPPDLPIR

4.30

-11.02

-9.31

EIPPPLPPK

4.81

-9.70

-7.99

PDLPIRLRK

5.81

-9.23

-7.53

P40343

PSPQPQPIH

9.09

-5.94

-4.24

APSDPPYPK

9.33

-1.37

0.33

ELAPSDPPY

9.92

-6.59

-4.88

Q03497

KFIPSRPAP

6.78

-8.01

-6.30

HKPKVKPSK

6.96

-9.04

-7.33

PLPPIPPTK

7.23

-7.24

-5.54

P53238

RPIPPAPTH

8.81

-6.21

-4.50

PIPPAPTHY

9.19

-5.73

-4.03

AGRPIPPAP

9.75

-6.52

-4.81

P40041

KIPLSPPSS

10.61

-5.91

-4.21

NGRTLPPVP

11.89

-5.37

-3.67

PLSPPSSSN

12.40

-3.56

-1.86

 


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