ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: HSE1_1GCQ-23.PDB
Scoring matrix: HSE1_1GCQ-23_mat
Uniprot code: P38753
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 15.53
Foldx random average score for Saccharomyces cerevisiae: 13.077

Available information for P38753 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 49
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2079
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5100
 Total fragments: 2198915
Proteins after random average filtering: 5100
 Total fragments: 1201625
Proteins after disorder filtering: 3382
 Total fragments: 75060
Proteins after pattern filtering: 1593
 Total fragments: 11128
Proteins after MINT filtering: 20
 Total fragments: 452


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

15.53

-1.79

0.00

Best peptides

KPRMPWY

0.00

-4.91

-3.12

         
Interactors      
Q07660

AFKPIGP

11.42

-6.05

-4.26

Q06604

GPRMPSR

5.97

-6.68

-4.89

KPTPPSP

6.17

-6.31

-4.52

KPKPTPP

6.83

-7.95

-6.16

Q06108

DPRSPYY

7.89

-3.46

-1.67

TPCKSPY

8.06

-6.07

-4.28

PPQPRRL

8.47

-5.41

-3.62

P40073

YPQQQPS

11.75

-3.99

-2.20

PQQQPSH

12.72

-3.00

-1.21

P25604

PHLKPPL

7.85

-6.90

-5.11

PPLPPPP

7.96

-6.86

-5.07

HLKPPLP

8.03

-9.22

-7.43

P40325

QPRPPPR

4.76

-5.73

-3.94

PPRPPRP

5.15

-6.36

-4.57

PPRPAAN

7.29

-5.33

-3.54

O13527

LPLPDLP

6.81

-8.30

-6.51

HPRGIPG

8.08

-5.38

-3.59

HPSMIPY

8.20

-6.40

-4.61

P48524

PKRKPLL

4.29

-8.06

-6.27

FPPKRKP

8.72

-7.58

-5.79

PLLRPQR

8.90

-8.26

-6.47

Q06412

ERRPPPP

5.61

-5.76

-3.97

RPPPPPP

6.66

-7.48

-5.69

RRPPPPP

6.75

-8.44

-6.65

Q66RC5

PDNPGRL

9.51

-3.97

-2.18

PLIPDNP

9.69

-5.48

-3.69

SPLIPDN

10.42

-6.22

-4.43

P36037

PPLKLPI

8.20

-7.01

-5.22

KPPLKLP

9.51

-7.37

-5.58

P36041

RMMPPPP

6.34

-8.81

-7.02

DLRPVIP

7.12

-5.53

-3.74

MPPPPPP

8.05

-7.24

-5.45

Q04439

NARPSPP

6.51

-6.24

-4.45

KPAPPPP

7.24

-6.20

-4.41

KPKEPMF

7.34

-6.83

-5.04

P53901

RPIPPLP

4.29

-8.69

-6.90

AMRPIPP

6.64

-6.03

-4.24

PKLPPLP

7.41

-7.20

-5.41

Q12446

RPLPQLP

4.73

-10.59

-8.80

HSLPPLP

6.41

-9.17

-7.38

NNRPVPP

6.70

-7.59

-5.80

P40453

RKRPPPP

2.26

-8.46

-6.67

KRPPPPP

6.61

-7.03

-5.24

RPPPPPP

6.66

-7.48

-5.69

P40343

SPQPQPI

10.26

-4.61

-2.82

QPQQPSP

10.47

-4.95

-3.16

PSDPPYP

11.04

-5.36

-3.57

Q03497

KFIPSRP

5.48

-7.67

-5.88

PSRPAPK

6.28

-5.70

-3.91

QPLPPIP

7.28

-7.32

-5.53

P53238

RPIPPAP

5.34

-8.19

-6.40

AGRPIPP

6.79

-5.89

-4.10

KPAGRPI

9.74

-3.07

-1.28

P40041

RTLPPVP

6.29

-8.65

-6.86

KIPLSPP

10.92

-5.33

-3.54

IPLSPPS

11.59

-4.12

-2.33

 


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