ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: HSE1_1GCQ-19.PDB
Scoring matrix: HSE1_1GCQ-19_mat
Uniprot code: P38753
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 17.56
Foldx random average score for Saccharomyces cerevisiae: 17.483

Available information for P38753 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 49
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2079
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5100
 Total fragments: 2188715
Proteins after random average filtering: 5100
 Total fragments: 1041833
Proteins after disorder filtering: 3177
 Total fragments: 49492
Proteins after pattern filtering: 1362
 Total fragments: 5395
Proteins after MINT filtering: 17
 Total fragments: 197


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

17.56

1.53

0.00

Best peptides

RRKLNGYRG

0.00

-1.18

-2.71

         
Interactors      
Q06604

PPSPPAKRI

10.74

-9.24

-10.77

PPPLPTRRD

12.32

-8.55

-10.08

GPRMPSRGR

12.50

-7.24

-8.77

Q06108

LMNLPGVSP

11.64

-7.49

-9.02

IRTPCKSPY

12.89

-5.46

-6.99

TDPPPQPRR

13.90

-6.37

-7.90

P25604

PPKPNTQLQ

15.12

-5.16

-6.69

DQAPSLPPK

15.28

-3.83

-5.36

PPKPKSPHL

15.58

-6.57

-8.10

P40325

HQSRPHQRP

13.77

-10.33

-11.86

RPPRPAANL

14.85

-8.03

-9.56

QPGDPRLGG

15.23

-2.57

-4.10

O13527

PRGIPGYAL

12.05

-5.09

-6.62

KIHPRGIPG

12.69

-4.76

-6.29

PLNPKGKKL

13.48

-6.21

-7.74

P48524

RKPLLRPQR

11.29

-5.87

-7.40

PKRKPLLRP

11.75

-9.25

-10.78

KRKPLLRPQ

13.81

-4.93

-6.46

Q06412

PPPPLLYST

15.03

-5.05

-6.58

GFSPNSPKS

16.02

-3.09

-4.62

PPPPLSTSR

16.12

-6.82

-8.35

Q66RC5

IPDNPGRLL

12.91

-5.24

-6.77

SPLIPDNPG

15.53

-3.51

-5.04

PDNPGRLLS

16.27

-2.52

-4.05

P36037

DGKPPLKLP

14.51

-6.60

-8.13

GKPPLKLPI

14.67

-4.47

-6.00

KPPLKLPIN

16.29

-7.70

-9.23

P36041

DLRPVIPRG

11.01

-5.42

-6.95

PMHPNFPNG

11.97

-5.14

-6.67

PPLPQGFPI

12.59

-6.41

-7.94

Q04439

IPTPPQNRD

14.86

-8.51

-10.04

PPPPSSKPK

14.92

-5.60

-7.13

APPPPGMQN

15.37

-5.60

-7.13

P53901

IPPLPTESE

15.00

-5.04

-6.57

PPLPTESEY

15.17

-3.13

-4.66

PNSHPHPSG

15.73

-4.61

-6.14

Q12446

PPPPTAETF

13.76

-5.05

-6.58

PPPPPHRHV

13.84

-8.54

-10.07

PPLPNQFAP

14.15

-7.74

-9.27

P40453

PDLPIRLRK

11.72

-5.78

-7.31

PPDLPIRLR

12.97

-7.53

-9.06

DCPRCGPTA

13.70

-4.07

-5.60

P40343

ELAPSDPPY

13.90

-5.76

-7.29

QPQQPSPQP

17.13

-5.32

-6.85

Q03497

KQHKPKVKP

14.51

-6.65

-8.18

IPSRPAPKP

14.61

-9.32

-10.85

GKFIPSRPA

14.91

-3.59

-5.12

P53238

PPAPTHYNN

14.26

-4.84

-6.37

RPIPPAPTH

15.15

-5.85

-7.38

 


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