ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: HSE1_1GCQ-18.PDB
Scoring matrix: HSE1_1GCQ-18_mat
Uniprot code: P38753
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAAA
Foldx wt ligand score: 19.51
Foldx random average score for Saccharomyces cerevisiae: 19.359

Available information for P38753 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 49
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2079
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5100
 Total fragments: 2183615
Proteins after random average filtering: 5100
 Total fragments: 1004643
Proteins after disorder filtering: 3174
 Total fragments: 73317
Proteins after pattern filtering: 1540
 Total fragments: 9113
Proteins after MINT filtering: 19
 Total fragments: 265


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAAA

19.51

5.27

0.00

Best peptides

FHPIRPRRGY

0.00

3.50

-1.77

         
Interactors      
Q06604

KGPRMPSRGR

8.16

-6.63

-11.90

LLPTRPNKAE

9.84

-2.14

-7.41

EKPLLPTRPN

13.56

-3.59

-8.86

Q06108

KSPYSPYTGE

11.61

-0.59

-5.86

KSTDPPPQPR

14.25

0.44

-4.83

ISKQPATPGS

14.70

-1.03

-6.30

P40073

FDGYPQQQPS

16.75

1.85

-3.42

P25604

APSLPPKPNT

14.93

-2.41

-7.68

PLPPKPKSPH

16.83

-0.46

-5.73

PPPPPPQPAS

17.42

-0.29

-5.56

P40325

LPWTYPPRFY

10.75

-2.99

-8.26

VQPGDPRLGG

12.63

-1.95

-7.22

QPPRPPRPAA

13.54

-3.26

-8.53

O13527

FPQYPSSVGT

11.78

-2.84

-8.11

LNVPLNPKGK

12.58

-2.66

-7.93

KIHPRGIPGY

12.70

-3.01

-8.28

P48524

KPLLRPQRSD

10.21

-4.29

-9.56

PKRKPLLRPQ

15.37

-4.03

-9.30

PLLRPQRSDF

15.52

2.74

-2.53

Q06412

FSPNSPKSPR

13.25

-0.59

-5.86

NSPKSPRDSS

13.40

1.67

-3.60

FTKPPPPLST

14.71

-0.94

-6.21

Q66RC5

SPLIPDNPGR

13.10

-2.73

-8.00

LIPDNPGRLL

17.62

-1.93

-7.20

PSPLIPDNPG

18.09

1.04

-4.23

P36037

KPPLKLPINV

14.31

-1.73

-7.00

PLKLPINVSD

15.49

-0.48

-5.75

P36041

YMPPPPPPGF

11.34

-3.87

-9.14

QRMMPPPPGL

11.89

-4.56

-9.83

QGPQFPVMGV

12.78

-2.25

-7.52

Q04439

KKPAPPPPGM

12.33

-2.94

-8.21

SKPKEPMFEA

14.90

1.04

-4.23

NNIPTPPQNR

15.70

0.00

-5.27

P53901

PNSHPHPSGL

14.04

-1.25

-6.52

PIILPPTFSA

15.02

-1.14

-6.41

KLPPLPTTSN

15.25

-0.15

-5.42

Q12446

KHSLPPLPNQ

11.82

-1.77

-7.04

PLPQLPNRNN

12.60

-3.69

-8.96

LPQLPNRNNR

12.79

-6.80

-12.07

P40453

KPPDLPIRLR

14.72

-1.69

-6.96

RPPPPPPVSM

14.90

-1.84

-7.11

NAWDCPRCGP

15.20

-1.94

-7.21

P40343

LAPSDPPYPK

14.89

-0.36

-5.63

SPQPQPIHSV

15.87

-0.40

-5.67

PSDPPYPKEE

18.94

3.80

-1.47

Q03497

LPPIPPTKSK

10.48

-3.06

-8.33

FPSKNPLKNS

11.84

-3.15

-8.42

KPSKPEAKSK

14.31

-1.07

-6.34

P53238

IPPAPTHYNN

16.89

-2.04

-7.31

KPAGRPIPPA

18.86

-1.42

-6.69

PIPPAPTHYN

18.88

1.73

-3.54

P40041

KIPLSPPSSS

14.51

-1.28

-6.55

IPLSPPSSSN

16.59

0.34

-4.93

PLSPPSSSNM

17.42

0.28

-4.99

 


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