ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: HSE1_1GCQ-17.PDB
Scoring matrix: HSE1_1GCQ-17_mat
Uniprot code: P38753
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 16.55
Foldx random average score for Saccharomyces cerevisiae: 16.477

Available information for P38753 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 49
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2079
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5100
 Total fragments: 2188715
Proteins after random average filtering: 5100
 Total fragments: 1060495
Proteins after disorder filtering: 3194
 Total fragments: 57790
Proteins after pattern filtering: 1450
 Total fragments: 6166
Proteins after MINT filtering: 18
 Total fragments: 205


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

16.55

-2.03

0.00

Best peptides

FPKMNGYRL

0.00

-10.54

-8.51

         
Interactors      
Q06604

LPTRPNKAE

11.29

-9.65

-7.62

GPRMPSRGR

11.73

-7.10

-5.07

EKGPRMPSR

11.84

-4.96

-2.93

Q06108

QPATPGSTR

9.24

-4.53

-2.50

TDPPPQPRR

11.04

-7.97

-5.94

KTDPRSPYY

12.13

-4.51

-2.48

P40073

GYPQQQPSH

13.55

-3.63

-1.60

P25604

LPPKPNTQL

10.99

-9.26

-7.23

PPKPNTQLQ

11.20

-4.99

-2.96

PPKPKSPHL

11.58

-6.55

-4.52

P40325

YVQPGDPRL

9.29

-9.27

-7.24

RPPRPAANL

10.84

-8.56

-6.53

LYVQPGDPR

12.29

-4.29

-2.26

O13527

PRGIPGYAL

10.05

-5.32

-3.29

PLNPKGKKL

10.14

-6.34

-4.31

MYFPPGPQS

12.08

-3.38

-1.35

P48524

FPPKRKPLL

7.87

-7.97

-5.94

PLLRPQRSD

12.36

-5.18

-3.15

KRKPLLRPQ

13.07

-3.49

-1.46

Q06412

PPPPLSTSR

11.33

-5.22

-3.19

PKSPRDSSK

12.27

-3.54

-1.51

PPPPLLYST

13.06

-4.11

-2.08

Q66RC5

IPDNPGRLL

10.87

-6.42

-4.39

PDNPGRLLS

15.73

-3.44

-1.41

NPSPLIPDN

16.02

-1.93

0.10

P36041

PPYPNMMLQ

10.16

-4.90

-2.87

PVIPRGPSS

10.61

-4.73

-2.70

FPIPPNGML

10.83

-8.93

-6.90

Q04439

APPPPGMQN

11.66

-5.56

-3.53

IPTPPQNRD

13.68

-7.71

-5.68

NNNIPTPPQ

13.74

-2.78

-0.75

P53901

MAMRPIPPL

12.18

-7.81

-5.78

RPIPPLPTE

12.26

-5.80

-3.77

PPLPPIPTR

12.29

-5.13

-3.10

Q12446

PPPPPRASR

10.66

-6.97

-4.94

RPLPQLPNR

11.96

-7.40

-5.37

APTTPAPAL

12.02

-5.28

-3.25

P40453

PDLPIRLRK

10.78

-6.44

-4.41

DCPRCGPTA

12.12

-4.15

-2.12

PPDLPIRLR

14.13

-6.50

-4.47

P40343

PQPQPIHSV

14.21

-3.99

-1.96

PSDPPYPKE

15.46

-3.56

-1.53

ELAPSDPPY

16.38

-5.17

-3.14

Q03497

PPIPPTKSK

10.09

-5.94

-3.91

HKPKVKPSK

11.09

-4.63

-2.60

PSKPEAKSK

12.42

-3.26

-1.23

P53238

RPIPPAPTH

11.91

-5.43

-3.40

PPAPTHYNN

14.24

-4.73

-2.70

IPPAPTHYN

14.82

-6.57

-4.54

P40041

PLSPPSSSN

14.32

-3.81

-1.78

 


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