ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: HSE1_1GCQ-15.PDB
Scoring matrix: HSE1_1GCQ-15_mat
Uniprot code: P38753
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 15.94
Foldx random average score for Saccharomyces cerevisiae: 11.959

Available information for P38753 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 49
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2079
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5100
 Total fragments: 2188715
Proteins after random average filtering: 5100
 Total fragments: 941928
Proteins after disorder filtering: 2827
 Total fragments: 30948
Proteins after pattern filtering: 1140
 Total fragments: 3717
Proteins after MINT filtering: 17
 Total fragments: 159


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

15.94

-0.42

0.00

Best peptides

RFFMIHKKR

0.00

-4.73

-4.31

         
Interactors      
Q06604

GPRMPSRGR

8.22

-6.64

-6.22

EEKPLLPTR

9.08

-3.25

-2.83

TPPSPPAKR

9.42

-6.67

-6.25

Q06108

TDPPPQPRR

9.64

-6.14

-5.72

NMPIPKKLP

10.14

-6.42

-6.00

TDPRSPYYI

10.82

-7.52

-7.10

P25604

KPKSPHLKP

8.41

-7.96

-7.54

LPPKPNTQL

11.20

-6.23

-5.81

PPLPPKPKS

11.27

-5.15

-4.73

P40325

HQSRPHQRP

8.21

-8.32

-7.90

RPHQRPSTM

8.33

-8.09

-7.67

RPPRPAANL

9.41

-8.87

-8.45

O13527

VPLNPKGKK

8.46

-5.01

-4.59

MIPYTPYQM

9.73

-5.50

-5.08

MSPMYFPPG

9.82

-6.39

-5.97

P48524

RKPLLRPQR

6.82

-10.71

-10.29

PPKRKPLLR

8.39

-9.11

-8.69

FPPKRKPLL

8.48

-6.39

-5.97

Q06412

PKLPPLNTR

9.70

-5.14

-4.72

PPPPLSTSR

10.25

-5.58

-5.16

SPNSPKSPR

10.93

-5.73

-5.31

Q66RC5

PLIPDNPGR

10.96

-5.70

-5.28

P36037

KPPLKLPIN

8.78

-8.08

-7.66

PPLKLPINV

11.68

-4.75

-4.33

P36041

NSPMPIPSI

9.38

-5.30

-4.88

HQGPQFPVM

9.42

-5.41

-4.99

GFFPMHPNF

9.58

-6.17

-5.75

Q04439

NIPTPPQNR

9.93

-6.62

-6.20

PPPSSKPKE

10.72

-5.05

-4.63

KPAPPPPGM

11.29

-6.05

-5.63

P53901

NDPIILPPT

10.12

-6.22

-5.80

PNSHPHPSG

10.16

-4.36

-3.94

PPIPTRDDM

10.26

-7.07

-6.65

Q12446

RPLPQLPNR

6.97

-6.08

-5.66

PPPPPHRHV

8.75

-8.29

-7.87

PPPPPRASR

9.38

-6.96

-6.54

P40453

WKPPDLPIR

8.48

-5.03

-4.61

PDLPIRLRK

9.27

-4.27

-3.85

PPDLPIRLR

9.42

-9.09

-8.67

P40343

PSPQPQPIH

11.71

-2.78

-2.36

Q03497

HKPKVKPSK

7.70

-4.24

-3.82

SFPSKNPLK

9.55

-4.56

-4.14

PIPPTKSKT

10.31

-5.43

-5.01

P53238

PPAPTHYNN

10.62

-6.93

-6.51

RPIPPAPTH

11.66

-6.11

-5.69

 


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