ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: HSE1_1GCQ-14.PDB
Scoring matrix: HSE1_1GCQ-14_mat
Uniprot code: P38753
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 15.32
Foldx random average score for Saccharomyces cerevisiae: 11.424

Available information for P38753 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 49
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2079
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5100
 Total fragments: 2188715
Proteins after random average filtering: 5100
 Total fragments: 951450
Proteins after disorder filtering: 2828
 Total fragments: 30405
Proteins after pattern filtering: 1198
 Total fragments: 3786
Proteins after MINT filtering: 19
 Total fragments: 149


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

15.32

-2.22

0.00

Best peptides

WPFLIFKKR

0.00

-7.06

-4.84

         
Interactors      
Q06604

GPRMPSRGR

8.07

-8.82

-6.60

TPPSPPAKR

8.27

-7.94

-5.72

PPPLPTRRD

8.40

-8.24

-6.02

Q06108

TDPPPQPRR

9.01

-6.86

-4.64

TDPRSPYYI

9.66

-7.20

-4.98

PPPQPRRLS

9.95

-5.14

-2.92

P40073

YPQQQPSHT

11.12

-5.24

-3.02

P25604

LPPKPNTQL

7.87

-8.78

-6.56

TPPLPPKPK

8.61

-7.24

-5.02

PKPKSPHLK

9.52

-7.26

-5.04

P40325

SLPWTYPPR

9.09

-7.12

-4.90

RPPRPAANL

9.17

-9.84

-7.62

RPHQRPSTM

9.17

-7.01

-4.79

O13527

NVPLNPKGK

8.61

-6.53

-4.31

VPLNPKGKK

8.65

-5.35

-3.13

FPPGPQSQF

9.38

-5.35

-3.13

P48524

RKPLLRPQR

3.73

-10.27

-8.05

PPKRKPLLR

5.47

-11.78

-9.56

KPLLRPQRS

7.37

-7.14

-4.92

Q06412

PPPPLSTSR

9.60

-8.01

-5.79

SPNSPKSPR

10.21

-6.06

-3.84

PKLPPLNTR

10.99

-7.91

-5.69

Q66RC5

PLIPDNPGR

10.27

-7.88

-5.66

P36037

KPPLKLPIN

6.66

-8.82

-6.60

PPLKLPINV

9.03

-6.36

-4.14

PLKLPINVS

9.09

-7.48

-5.26

P36041

PPNFPQRMM

8.31

-6.13

-3.91

GVPPNFPQR

8.72

-7.78

-5.56

QPPYPNMML

9.08

-4.07

-1.85

Q04439

KPKEPMFEA

9.40

-4.37

-2.15

NIPTPPQNR

10.24

-6.83

-4.61

PPPPGMQNK

10.48

-6.82

-4.60

P53901

LPPLPTTSN

9.00

-6.92

-4.70

QPPLPPIPT

9.33

-7.47

-5.25

PPLPPIPTR

9.63

-9.59

-7.37

Q12446

LPPLPNQFA

6.83

-8.65

-6.43

LPQLPNRNN

7.65

-8.89

-6.67

PFPVPQQQF

8.41

-7.03

-4.81

P40453

PPDLPIRLR

4.73

-11.79

-9.57

WKPPDLPIR

8.95

-8.30

-6.08

PPPVSMPTT

9.11

-7.86

-5.64

P40343

PSPQPQPIH

11.13

-4.40

-2.18

PQPQPIHSV

11.16

-4.66

-2.44

Q03497

SFPSKNPLK

8.89

-4.29

-2.07

HKPKVKPSK

9.23

-4.10

-1.88

FPSKNPLKN

9.85

-6.99

-4.77

P53238

PPAPTHYNN

10.37

-6.99

-4.77

P40041

KIPLSPPSS

9.87

-5.75

-3.53

 


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