ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: HSE1_1GCQ-11.PDB
Scoring matrix: HSE1_1GCQ-11_mat
Uniprot code: P38753
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 13.85
Foldx random average score for Saccharomyces cerevisiae: 10.697

Available information for P38753 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 49
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2079
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5100
 Total fragments: 2198915
Proteins after random average filtering: 5100
 Total fragments: 952185
Proteins after disorder filtering: 3319
 Total fragments: 69518
Proteins after pattern filtering: 1616
 Total fragments: 9603
Proteins after MINT filtering: 19
 Total fragments: 389


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

13.85

1.06

0.00

Best peptides

FDPKPGR

0.00

-5.21

-6.27

         
Interactors      
Q06604

KPLLPTR

3.96

-8.35

-9.41

PPPLPTR

4.48

-9.18

-10.24

GPRMPSR

4.51

-7.65

-8.71

Q06108

PPPQPRR

4.85

-9.76

-10.82

TDPPPQP

6.72

-3.95

-5.01

PIPKKLP

7.38

-6.06

-7.12

P40073

PQQQPSH

6.94

-5.02

-6.08

YPQQQPS

9.28

-3.36

-4.42

GYPQQQP

9.96

-2.50

-3.56

P25604

PHLKPPL

4.21

-5.73

-6.79

LPPKPKS

5.41

-7.75

-8.81

TPPLPPK

5.47

-7.40

-8.46

P40325

QPPRPPR

4.04

-10.08

-11.14

PPPRPQQ

4.80

-10.34

-11.40

RPPRPAA

5.93

-8.26

-9.32

O13527

NVPLNPK

6.80

-5.34

-6.40

VPENPHH

6.91

-4.33

-5.39

IPYTPYQ

6.92

-5.36

-6.42

P48524

PLLRPQR

4.09

-7.65

-8.71

PKRKPLL

4.11

-6.74

-7.80

FPPKRKP

6.08

-6.59

-7.65

Q06412

NSPKSPR

5.96

-3.67

-4.73

PPPPPPL

6.40

-7.51

-8.57

TKPPPPL

6.72

-4.76

-5.82

Q66RC5

IPDNPGR

5.46

-8.00

-9.06

SPLIPDN

7.45

-5.71

-6.77

PDNPGRL

8.94

-3.57

-4.63

P36037

PLKLPIN

6.43

-7.04

-8.10

KPPLKLP

8.14

-6.49

-7.55

PPLKLPI

8.20

-6.13

-7.19

P36041

MPPPPGL

5.27

-7.06

-8.12

PPNFPQR

5.71

-7.28

-8.34

NGPMPPL

5.91

-5.72

-6.78

Q04439

APPPPGM

5.97

-7.32

-8.38

NIPTPPQ

6.55

-5.34

-6.40

PSSKPKE

6.88

-5.26

-6.32

P53901

LPPIPTR

4.74

-7.84

-8.90

MRPIPPL

4.76

-5.02

-6.08

SPKLPPL

5.92

-7.01

-8.07

Q12446

LPQLPNR

4.84

-7.90

-8.96

LPPLPNQ

5.31

-8.48

-9.54

PPPPPHR

5.44

-9.60

-10.66

P40453

PPDLPIR

4.90

-8.74

-9.80

PPPLPPK

5.06

-9.46

-10.52

KRPPPPP

6.86

-6.77

-7.83

P40343

PQPQPIH

6.58

-5.74

-6.80

PSPQPQP

7.07

-5.45

-6.51

QPQQPSP

7.99

-5.51

-6.57

Q03497

PKVKPSK

3.83

-7.23

-8.29

FPSKNPL

4.45

-5.80

-6.86

KPSKPEA

5.84

-7.57

-8.63

P53238

IPPAPTH

6.53

-5.25

-6.31

PAGRPIP

7.61

-6.96

-8.02

RPIPPAP

7.71

-6.50

-7.56

P40041

RTLPPVP

7.99

-4.95

-6.01

KIPLSPP

8.55

-4.44

-5.50

IPLSPPS

8.57

-3.96

-5.02

 


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