ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1SHF-8.PDB
Scoring matrix: FUS1_1SHF-8_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 15.55
Foldx random average score for Saccharomyces cerevisiae: 11.567

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3214216
Proteins after random average filtering: 7178
 Total fragments: 1287073
Proteins after disorder filtering: 4201
 Total fragments: 48975
Proteins after pattern filtering: 2022
 Total fragments: 9650
Proteins after MINT filtering: 22
 Total fragments: 166


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

15.55

1.10

0.00

Best peptides

HRRPWPPR

0.00

-2.23

-3.33

         
Interactors      
P36119

TRPTVQPS

9.14

-2.13

-3.23

TTRPTVQP

10.29

-3.10

-4.20

P53950

PLLPLPSL

6.93

-6.09

-7.19

PPAPLLPL

8.06

-2.96

-4.06

PAPLLPLP

9.58

-3.86

-4.96

P40073

YPQQQPSH

10.59

-3.24

-4.34

P24583

ANAPLPPQ

7.61

-3.95

-5.05

PLPPQPRK

9.35

-4.56

-5.66

APLPPQPR

10.65

-0.94

-2.04

P53947

PFNPIQDP

10.15

-3.68

-4.78

FNPIQDPF

11.34

-1.76

-2.86

ASPFNPIQ

11.53

-1.19

-2.29

Q03466

PMAPDTFN

11.15

-2.42

-3.52

P34250

YPKEPPAR

8.39

-3.15

-4.25

SNPDLPTA

9.52

-3.71

-4.81

PKPAYVPP

9.60

-2.66

-3.76

Q12280

VTPPLRPQ

8.34

-3.09

-4.19

GSPSKPGN

11.15

-1.95

-3.05

PLRPQSSS

11.44

-2.28

-3.38

P39732

TRHPSIAP

8.24

-3.46

-4.56

SRSPSVSP

9.00

-3.11

-4.21

SPSVSPVR

10.89

-1.64

-2.74

P40091

QNPSHPHH

10.57

-2.43

-3.53

SQNPSHPH

11.15

-0.43

-1.53

P40450

SPKLFPRL

6.88

-3.14

-4.24

APPPLPDL

6.94

-4.24

-5.34

KLPQLPPP

8.19

-5.97

-7.07

P25376

DRPSSQPH

8.64

-0.44

-1.54

RPSSQPHL

10.29

-2.50

-3.60

P41832

PPPPLPSV

8.06

-4.19

-5.29

VIPPAPPM

8.11

-3.79

-4.89

PPPPVPAK

9.04

-3.62

-4.72

P31374

TPDDLPPL

7.96

-3.10

-4.20

EQPRLPST

8.64

-4.12

-5.22

KKPGTPVF

8.72

-2.98

-4.08

P32917

YSPLLPPF

7.58

-4.44

-5.54

SRFPPYSP

7.98

-1.57

-2.67

NIPPKVAP

9.18

-3.52

-4.62

P40020

VLPPLPFP

8.07

-6.33

-7.43

DRPPPLTP

8.15

-2.85

-3.95

SRVLPPLP

8.31

-2.44

-3.54

P16892

GEPIPPSF

10.63

-2.75

-3.85

EGEPIPPS

11.37

-1.61

-2.71

P40210

VDPTEPQT

11.52

-1.71

-2.81

Q12114

EPVGTPNI

10.36

-1.50

-2.60

P21268

PISPPPSL

9.56

-2.03

-3.13

SKPISPPP

9.92

-3.26

-4.36

LSKPISPP

10.86

-1.45

-2.55

Q12753

HRYPPMAP

7.34

-3.86

-4.96

PRMPKTGS

8.20

-3.01

-4.11

SIPQSPPL

8.83

-3.33

-4.43

P14681

DEPEYPPL

9.36

-2.56

-3.66

DPSDEPEY

10.81

-1.72

-2.82

PEYPPLNL

11.22

-2.01

-3.11

 


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