ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1SHF-7.PDB
Scoring matrix: FUS1_1SHF-7_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAA
Foldx wt ligand score: 11.12
Foldx random average score for Saccharomyces cerevisiae: 9.164

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3214216
Proteins after random average filtering: 7178
 Total fragments: 1379953
Proteins after disorder filtering: 4571
 Total fragments: 68372
Proteins after pattern filtering: 2138
 Total fragments: 11877
Proteins after MINT filtering: 21
 Total fragments: 187


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AGAAAAAA

11.12

-0.40

0.00

Best peptides

WRPMMPKR

0.00

-3.70

-3.30

         
Interactors      
Q12280

INTAPASP

7.45

-3.66

-3.26

TPPLRPQS

8.19

-2.86

-2.46

YSGSPSKP

8.30

-2.12

-1.72

P31374

TKPPPPLD

4.86

-3.26

-2.86

RKTKPPPP

6.66

-3.88

-3.48

ISPERPSF

6.66

-1.08

-0.68

P36119

TRPTVQPS

9.02

-2.52

-2.12

P40073

PQQQPSHT

8.68

-2.71

-2.31

P24583

LPPQPRKH

5.17

-5.42

-5.02

PLPPQPRK

6.85

-2.69

-2.29

ANAPLPPQ

7.68

-3.43

-3.03

P39732

PSVSPVRT

8.41

-2.48

-2.08

RHPSIAPP

8.43

-2.17

-1.77

PSIAPPSK

8.55

-2.19

-1.79

P21268

LSKPISPP

7.63

-3.60

-3.20

KPISPPPS

8.00

-2.83

-2.43

PISPPPSL

8.74

-1.68

-1.28

P40091

QNPSHPHH

7.02

-1.22

-0.82

NPSHPHHN

7.97

-1.86

-1.46

WDPSSPSS

8.92

-0.30

0.10

P40450

PKLFPRLS

5.29

-4.23

-3.83

PPPPPPLP

6.86

-3.88

-3.48

APAPPPLP

7.15

-3.43

-3.03

P32917

IPPKVAPF

6.43

-3.63

-3.23

LPQHPHRT

6.83

-3.66

-3.26

FPPYSPLL

6.97

-1.79

-1.39

P25376

PSSQPHLG

7.15

-2.82

-2.42

DRPSSQPH

8.39

-0.29

0.11

RPSSQPHL

8.66

-0.95

-0.55

P40020

DRPPPLTP

7.01

-2.11

-1.71

SRVLPPLP

7.16

-6.37

-5.97

NPHSIPFS

7.29

-1.62

-1.22

P41832

IPPAPPMM

4.84

-4.73

-4.33

PPPPMALF

5.63

-3.62

-3.22

PPPPPPMA

6.16

-3.72

-3.32

P16892

EGEPIPPS

8.28

-1.97

-1.57

PNDEPEGE

8.62

-2.48

-2.08

GEPIPPSF

9.00

-2.69

-2.29

Q03466

VPMAPDTF

8.23

-2.09

-1.69

SSVPMAPD

8.30

-1.92

-1.52

P14681

EPEYPPLN

6.50

-2.97

-2.57

P53046

LSTPPTPK

7.14

-3.66

-3.26

STPPTPKS

7.60

-2.57

-2.17

P53947

ASPFNPIQ

7.97

-2.15

-1.75

SPFNPIQD

8.33

-1.95

-1.55

FNPIQDPF

8.90

-2.44

-2.04

Q12753

INSPRMPK

4.90

-4.14

-3.74

NSPRMPKT

5.42

-4.03

-3.63

IPQSPPLS

5.61

-4.03

-3.63

P34250

PKEPPARK

5.28

-4.14

-3.74

YPKEPPAR

7.36

-2.39

-1.99

KPAYVPPE

7.84

-2.12

-1.72

P53950

PNGAPLRR

5.88

-4.74

-4.34

PNPSIPSA

7.36

-2.46

-2.06

SNTPPAPL

7.55

-3.08

-2.68

 


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