ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1SHF-6.PDB
Scoring matrix: FUS1_1SHF-6_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 13.24
Foldx random average score for Saccharomyces cerevisiae: 9.777

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3199860
Proteins after random average filtering: 7178
 Total fragments: 1378472
Proteins after disorder filtering: 4014
 Total fragments: 51674
Proteins after pattern filtering: 2134
 Total fragments: 14046
Proteins after MINT filtering: 22
 Total fragments: 218


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

13.24

-1.05

0.00

Best peptides

HRRIKRMRPK

0.00

-2.30

-1.24

         
Interactors      
P36119

STTRPTVQPS

7.61

-3.46

-2.41

PTVQPSNQST

9.16

-2.03

-0.97

RPTVQPSNQS

9.34

-2.80

-1.74

P53950

TKTAPSTAPL

7.13

-4.22

-3.17

TPPAPLLPLP

7.21

-3.79

-2.74

PNGAPLRRYS

7.96

-4.11

-3.06

P40073

FDGYPQQQPS

9.72

-2.73

-1.68

DGYPQQQPSH

9.75

-2.79

-1.74

P24583

LPPQPRKHDK

5.69

-5.64

-4.59

NAPLPPQPRK

8.10

-6.59

-5.54

PPQPRKHDKT

8.21

-4.22

-3.17

P53947

SPFNPIQDPF

9.25

-3.37

-2.32

FNPIQDPFTD

9.39

-3.12

-2.07

P34250

YHSKKPSNPP

6.96

-2.86

-1.80

HSKKPSNPPS

7.24

-3.20

-2.15

ALYPKEPPAR

7.75

-3.96

-2.91

P53046

TPPTPKSAGH

8.71

-4.02

-2.96

PPTPKSAGHT

9.59

-2.94

-1.89

LSTPPTPKSA

9.70

-3.26

-2.21

Q12280

TNVTPPLRPQ

5.87

-4.07

-3.02

NVTPPLRPQS

6.38

-5.21

-4.16

PPLRPQSSSK

7.63

-4.24

-3.19

P39732

STRHPSIAPP

7.49

-5.41

-4.36

NSTRHPSIAP

7.99

-2.99

-1.94

TRHPSIAPPS

8.23

-1.85

-0.80

P40091

NPSHPHHNSR

8.47

-5.88

-4.83

QNPSHPHHNS

9.62

-3.08

-2.03

P40450

PKLFPRLSSD

5.59

-4.59

-3.54

APAPPPLPDL

6.98

-4.66

-3.61

PPPPPPLPES

7.30

-5.35

-4.29

P25376

SNDRPSSQPH

6.99

-3.28

-2.22

RPSSQPHLGY

9.52

-4.26

-3.21

P41832

TPPPPPLPSV

6.63

-5.01

-3.96

PPPPPPMALF

7.22

-5.63

-4.58

PPPPPPVPAK

7.31

-5.14

-4.09

Q03466

GSSVPMAPDT

9.43

-3.86

-2.80

P31374

TKPPPPLDFE

5.60

-5.26

-4.21

FRKTKPPPPL

5.72

-4.99

-3.94

DFEQPRLPST

5.77

-5.26

-4.21

P32917

DNIPPKVAPF

6.57

-4.62

-3.57

SRFPPYSPLL

6.65

-4.61

-3.56

YLPQHPHRTS

6.87

-5.05

-4.00

P40020

SRVLPPLPFP

5.08

-5.86

-4.81

DRPPPLTPEK

5.27

-6.11

-5.06

CVNPHSIPFS

6.56

-3.98

-2.92

Q12114

LKSEPVGTPN

8.34

-3.98

-2.92

P40210

DPTEPQTNDS

9.43

-3.45

-2.40

P21268

NLSKPISPPP

7.40

-4.33

-3.28

PISPPPSLKK

7.59

-4.31

-3.25

LNLSKPISPP

7.68

-2.68

-1.63

Q12753

NHRYPPMAPT

4.99

-5.06

-4.00

MIKPKGRPST

5.86

-5.17

-4.12

LMMIKPKGRP

6.00

-4.74

-3.69

P14681

EPEYPPLNLD

8.30

-5.34

-4.29

PSDEPEYPPL

9.31

-3.07

-2.01

 


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