ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1SHF-5.PDB
Scoring matrix: FUS1_1SHF-5_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 22.19
Foldx random average score for Saccharomyces cerevisiae: 17.339

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3199860
Proteins after random average filtering: 7178
 Total fragments: 1374437
Proteins after disorder filtering: 4487
 Total fragments: 74494
Proteins after pattern filtering: 2146
 Total fragments: 13306
Proteins after MINT filtering: 23
 Total fragments: 181


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

22.19

1.29

0.00

Best peptides

KWWWPRPPRM

0.00

-0.86

-2.15

         
Interactors      
P36119

TRPTVQPSNQ

13.31

-4.99

-6.28

SSTTRPTVQP

14.35

-6.56

-7.85

P53950

IGSNTPPAPL

11.73

-5.99

-7.28

IFDSNPNGAP

13.50

-7.75

-9.04

GSNTPPAPLL

13.58

-4.01

-5.30

P40073

GYPQQQPSHT

13.07

-7.37

-8.66

QFDGYPQQQP

14.13

-8.07

-9.36

DGYPQQQPSH

15.87

-1.81

-3.10

P24583

ERANAPLPPQ

13.37

-6.32

-7.61

RANAPLPPQP

13.43

-6.74

-8.03

NAPLPPQPRK

13.81

-4.47

-5.76

P53947

ASPFNPIQDP

14.77

-7.58

-8.87

FNPIQDPFTD

16.63

-2.22

-3.51

PFNPIQDPFT

16.83

-4.54

-5.83

P34250

LYPKEPPARK

7.69

-6.72

-8.01

YHSKKPSNPP

11.60

-6.61

-7.90

PYHSKKPSNP

12.01

-9.30

-10.59

P53046

LSTPPTPKSA

14.98

-4.19

-5.48

QLSTPPTPKS

15.42

-1.53

-2.82

NQLSTPPTPK

15.45

-4.85

-6.14

Q12280

YSGSPSKPGN

14.96

-2.24

-3.53

TNVTPPLRPQ

16.08

-6.92

-8.21

TAYSGSPSKP

16.58

-6.01

-7.30

P39732

RSPSVSPVRT

11.38

-6.87

-8.16

RHPSIAPPSK

12.75

-7.01

-8.30

NSSRSPSVSP

13.85

-5.13

-6.42

P40091

FGMSSPASSP

12.64

-5.60

-6.89

PSHPHHNSRP

13.20

-7.29

-8.58

TWDPSSPSSV

14.80

-1.18

-2.47

P40450

KLPQLPPPPP

10.04

-6.39

-7.68

CGAVPPPPPP

12.73

-6.93

-8.22

VSSSPKLFPR

12.88

-3.26

-4.55

P25376

DRPSSQPHLG

13.87

-4.28

-5.57

GSNDRPSSQP

14.66

-5.43

-6.72

P41832

LSSQPPPPPP

8.22

-7.20

-8.49

KGETPPPPPL

9.51

-6.74

-8.03

DSPAPPPPPP

10.29

-6.97

-8.26

Q03466

YSGSSVPMAP

12.57

-6.71

-8.00

SGSSVPMAPD

16.51

-4.87

-6.16

GSSVPMAPDT

17.02

-3.76

-5.05

P31374

ISPERPSFRQ

9.23

-4.40

-5.69

FRKTKPPPPL

9.78

-8.76

-10.05

LSNKKPGTPV

10.91

-2.97

-4.26

P32917

YSPLLPPFGL

10.93

-5.08

-6.37

QSRFPPYSPL

11.40

-4.58

-5.87

VSTDYLPQHP

12.41

-7.50

-8.79

P40020

KSRVLPPLPF

8.31

-5.63

-6.92

ISLPPYLSPQ

10.64

-3.31

-4.60

KKSRVLPPLP

10.91

-5.09

-6.38

P16892

TYHDPNDEPE

15.27

-6.19

-7.48

P40210

HDEVDPTEPQ

16.30

-2.52

-3.81

Q12114

KSEPVGTPNI

14.72

-2.16

-3.45

GHETAPVSPV

15.64

-4.90

-6.19

LKSEPVGTPN

16.88

-5.05

-6.34

P21268

LNLSKPISPP

13.28

-8.82

-10.11

KPISPPPSLK

13.34

-7.88

-9.17

SKPISPPPSL

14.21

-4.67

-5.96

Q12753

LMMIKPKGRP

11.38

-8.38

-9.67

IKPKGRPSTT

11.72

-5.23

-6.52

QSINSPRMPK

11.99

-3.49

-4.78

P14681

PSDEPEYPPL

17.17

-2.75

-4.04

 


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