ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1SHF-26.PDB
Scoring matrix: FUS1_1SHF-26_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 19.57
Foldx random average score for Saccharomyces cerevisiae: 14.060

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3207038
Proteins after random average filtering: 7178
 Total fragments: 1353831
Proteins after disorder filtering: 4240
 Total fragments: 61780
Proteins after pattern filtering: 2088
 Total fragments: 12101
Proteins after MINT filtering: 20
 Total fragments: 203


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

19.57

0.65

0.00

Best peptides

YRRRRWMPR

0.00

-5.48

-6.13

         
Interactors      
Q12280

VTPPLRPQS

10.07

-3.96

-4.61

PPLRPQSSS

10.94

-3.01

-3.65

PLRPQSSSK

11.29

-0.96

-1.61

P31374

PERPSFRQP

10.05

-4.23

-4.88

FRKTKPPPP

10.67

-3.22

-3.87

DFEQPRLPS

11.62

-2.78

-3.42

P36119

TTRPTVQPS

9.35

-2.72

-3.37

TRPTVQPSN

13.25

-2.50

-3.15

PTVQPSNQS

13.39

0.11

-0.54

P40073

DGYPQQQPS

10.98

-2.70

-3.35

GYPQQQPSH

13.74

-3.23

-3.88

P24583

APLPPQPRK

10.45

-3.99

-4.63

NAPLPPQPR

11.26

-3.55

-4.20

LPPQPRKHD

12.21

-3.55

-4.20

P39732

RSPSVSPVR

9.99

-3.59

-4.23

RHPSIAPPS

12.03

-1.80

-2.45

STRHPSIAP

12.38

-3.42

-4.06

P21268

LSKPISPPP

10.95

-3.30

-3.94

SKPISPPPS

11.53

-1.59

-2.24

KPISPPPSL

12.36

-3.63

-4.28

P40091

PSHPHHNSR

10.23

-4.58

-5.22

VTWDPSSPS

12.40

-0.78

-1.43

TWDPSSPSS

12.46

-0.78

-1.43

P40450

PKLFPRLSS

8.37

-6.93

-7.57

SSSPKLFPR

10.23

-4.73

-5.38

PPPPPLPES

10.70

-3.78

-4.42

P32917

DYLPQHPHR

9.67

-6.05

-6.70

QSRFPPYSP

10.93

-5.68

-6.32

PQHPHRTSS

11.14

-1.86

-2.50

P25376

NDRPSSQPH

9.84

-3.54

-4.19

DRPSSQPHL

13.88

-1.78

-2.42

P40020

FDRPPPLTP

9.39

-4.72

-5.37

RVLPPLPFP

10.30

-5.44

-6.09

SEEPTSPTR

10.71

-3.09

-3.73

P41832

PPLPSVLSS

10.40

-3.88

-4.53

PAPPMMPAS

10.46

-4.12

-4.77

TPPPPPLPS

11.29

-2.58

-3.23

P16892

EGEPIPPSF

13.38

-1.87

-2.52

PEGEPIPPS

13.96

-2.95

-3.60

P53947

FNPIQDPFT

13.82

-1.36

-2.00

P34250

LYPKEPPAR

9.59

-4.58

-5.22

SKKPSNPPS

10.85

-3.32

-3.96

HSKKPSNPP

11.36

-2.51

-3.15

P14681

PEYPPLNLD

12.11

-2.47

-3.12

SDEPEYPPL

13.09

-3.00

-3.65

HDPSDEPEY

13.72

-1.46

-2.11

Q12753

FSIPQSPPL

9.25

-3.81

-4.46

MIKPKGRPS

9.86

-2.25

-2.90

NHRYPPMAP

10.62

-4.86

-5.51

P53046

LSTPPTPKS

13.01

-2.27

-2.92

NQLSTPPTP

13.98

-2.90

-3.54

P53950

APLLPLPSL

11.14

-5.07

-5.71

NPNGAPLRR

12.49

-4.77

-5.41

PAPLLPLPS

12.56

-1.71

-2.36

 


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