ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1SHF-23.PDB
Scoring matrix: FUS1_1SHF-23_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 15.65
Foldx random average score for Saccharomyces cerevisiae: 11.615

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3221394
Proteins after random average filtering: 7178
 Total fragments: 1465524
Proteins after disorder filtering: 4641
 Total fragments: 65691
Proteins after pattern filtering: 1975
 Total fragments: 9165
Proteins after MINT filtering: 18
 Total fragments: 153


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

15.65

-0.60

0.00

Best peptides

NEMFPRM

0.00

-4.54

-3.94

         
Interactors      
Q12280

VTPPLRP

8.68

-3.56

-2.96

PPLRPQS

9.56

-3.25

-2.65

TPPLRPQ

9.59

-3.50

-2.90

P31374

NISPERP

7.11

-2.97

-2.37

KTKPPPP

8.89

-3.79

-3.19

QPRLPST

8.99

-3.22

-2.62

P36119

RPTVQPS

9.84

-4.68

-4.08

P24583

LPPQPRK

6.19

-5.54

-4.94

NAPLPPQ

8.06

-3.31

-2.71

PPQPRKH

9.93

-2.68

-2.08

P21268

LSKPISP

9.34

-3.83

-3.23

KPISPPP

10.15

-3.59

-2.99

P40091

NPSHPHH

9.87

-1.93

-1.33

P40450

PKLFPRL

3.98

-5.72

-5.12

LPQLPPP

7.65

-4.59

-3.99

SPKLFPR

8.54

-4.19

-3.59

P32917

SPLLPPF

7.54

-4.66

-4.06

LPQHPHR

8.55

-4.55

-3.95

PQHPHRT

8.56

-2.47

-1.87

P40020

LPPLPFP

8.17

-5.20

-4.60

RVLPPLP

8.44

-4.74

-4.14

PPLPFPL

8.58

-4.02

-3.42

P41832

PPMMPAS

9.07

-4.99

-4.39

PPLPSVL

9.29

-3.49

-2.89

TPPPPPL

9.62

-2.26

-1.66

P16892

EPIPPSF

8.72

-3.35

-2.75

Q03466

VPMAPDT

10.94

-4.07

-3.47

P14681

EPEYPPL

9.75

-2.06

-1.46

PEYPPLN

10.48

-3.20

-2.60

P53046

LSTPPTP

10.90

-3.80

-3.20

P53947

NPIQDPF

8.21

-3.04

-2.44

ASPFNPI

10.10

-2.59

-1.99

Q12753

IKPKGRP

7.96

-4.24

-3.64

NSPRMPK

8.25

-2.37

-1.77

FSIPQSP

10.42

-4.17

-3.57

P34250

KPAYVPP

9.47

-4.56

-3.96

PDLPTAL

9.50

-4.08

-3.48

LYPKEPP

10.26

-3.05

-2.45

P53950

NTPPAPL

8.86

-2.48

-1.88

APLLPLP

8.95

-5.10

-4.50

PAPLLPL

9.77

-3.20

-2.60

 


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