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Matrix information:
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ADAN-name: FUS1_1SHF-21.PDB
Scoring matrix: FUS1_1SHF-21_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAGGAAAA
Foldx wt ligand score: 13.27
Foldx random average score for Saccharomyces cerevisiae: 12.660 Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
Proteins belonging to other specie: 0
Nš of interactions described: 47
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
Total fragments: 3199860
Proteins after random average filtering: 7178
Total fragments: 1888382
Proteins after disorder filtering: 4442
Total fragments: 73532
Proteins after pattern filtering: 1743
Total fragments: 4639
Proteins after MINT filtering: 20
Total fragments: 64
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAGGAAAA |
13.27
|
-0.05 |
0.00 |
| Best peptides |
RWRRGIPTFL |
0.00
|
0.58 |
0.63 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| Q12280 |
PLRPQSSSKI |
7.79
|
-2.79 |
-2.74 |
|
SGSPSKPGNN |
11.07
|
-0.86 |
-0.81 |
|
PSKPGNNNSY |
11.68
|
-1.98 |
-1.93 |
| P31374 |
NISPERPSFR |
6.74
|
-3.20 |
-3.15 |
|
VFPNLDPTHS |
9.52
|
-3.46 |
-3.41 |
|
FEQPRLPSTA |
10.10
|
-0.90 |
-0.85 |
| P36119 |
TRPTVQPSNQ |
11.41
|
-2.30 |
-2.25 |
|
RPTVQPSNQS |
12.25
|
-1.70 |
-1.65 |
| P40073 |
GYPQQQPSHT |
7.85
|
-2.63 |
-2.58 |
| P24583 |
PPQPRKHDKT |
9.10
|
-3.54 |
-3.49 |
|
PLPPQPRKHD |
12.37
|
-3.40 |
-3.35 |
| P39732 |
HPSIAPPSKL |
7.29
|
-4.13 |
-4.08 |
|
SPSVSPVRTT |
11.17
|
-6.15 |
-6.10 |
|
RSPSVSPVRT |
11.20
|
-4.08 |
-4.03 |
| P40091 |
SQNPSHPHHN |
8.96
|
-2.55 |
-2.50 |
|
TWDPSSPSSV |
9.21
|
-0.87 |
-0.82 |
|
SPASSPVTWD |
12.45
|
-0.85 |
-0.80 |
| P40450 |
SSPKLFPRLS |
9.50
|
-6.23 |
-6.18 |
|
PPLPESLSMN |
9.53
|
-2.55 |
-2.50 |
|
PPPPLPQSLL |
9.87
|
-3.85 |
-3.80 |
| P32917 |
DYLPQHPHRT |
7.15
|
-2.43 |
-2.38 |
|
PQHPHRTSSL |
10.14
|
-1.66 |
-1.61 |
|
YLPQHPHRTS |
10.21
|
-5.43 |
-5.38 |
| P25376 |
DRPSSQPHLG |
10.96
|
-2.66 |
-2.61 |
| P40020 |
SEEPTSPTRQ |
8.35
|
-2.59 |
-2.54 |
|
RPPPLTPEKN |
9.73
|
-1.72 |
-1.67 |
|
PPYLSPQNKD |
10.31
|
-2.94 |
-2.89 |
| P41832 |
PPLPSVLSSS |
12.57
|
-0.50 |
-0.45 |
| Q12114 |
SEPVGTPNIE |
10.79
|
-3.26 |
-3.21 |
| Q03466 |
SVPMAPDTFN |
9.48
|
-3.33 |
-3.28 |
|
PMAPDTFNVK |
10.13
|
-2.22 |
-2.17 |
|
SSVPMAPDTF |
10.77
|
-1.50 |
-1.45 |
| P53046 |
PPTPKSAGHT |
10.28
|
-2.27 |
-2.22 |
| P53947 |
NPIQDPFTDN |
11.50
|
-0.48 |
-0.43 |
|
FNPIQDPFTD |
11.71
|
-1.43 |
-1.38 |
| Q12753 |
IKPKGRPSTT |
6.82
|
-1.05 |
-1.00 |
|
RYPPMAPTTV |
7.46
|
-2.22 |
-2.17 |
|
PRMPKTGSRQ |
8.33
|
-3.24 |
-3.19 |
| P34250 |
LYPKEPPARK |
7.58
|
-5.54 |
-5.49 |
|
SSNPDLPTAL |
9.22
|
-2.30 |
-2.25 |
| P53950 |
NPNGAPLRRY |
10.94
|
-4.96 |
-4.91 |
|
PSIPSASTST |
11.08
|
-0.21 |
-0.16 |
|
APNPSIPSAS |
11.12
|
-1.46 |
-1.41 |
| P40210 |
EVDPTEPQTN |
10.86
|
-1.73 |
-1.68 |
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