ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1SHF-20.PDB
Scoring matrix: FUS1_1SHF-20_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 16.7
Foldx random average score for Saccharomyces cerevisiae: 16.303

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3207038
Proteins after random average filtering: 7178
 Total fragments: 1636870
Proteins after disorder filtering: 4575
 Total fragments: 76573
Proteins after pattern filtering: 1886
 Total fragments: 5849
Proteins after MINT filtering: 20
 Total fragments: 76


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

16.70

0.67

0.00

Best peptides

LRKERRMWR

0.00

0.18

-0.49

         
Interactors      
Q12280

SPSKPGNNN

15.33

-1.53

-2.20

YSGSPSKPG

15.54

-0.25

-0.92

VTPPLRPQS

15.55

-1.44

-2.11

P31374

NISPERPSF

13.15

-1.42

-2.09

ISPERPSFR

13.29

-4.92

-5.59

FEQPRLPST

13.67

-3.23

-3.90

P36119

TRPTVQPSN

13.57

0.03

-0.64

P40073

GYPQQQPSH

15.08

-2.58

-3.25

P24583

LPPQPRKHD

11.11

-5.37

-6.04

RANAPLPPQ

15.29

-2.88

-3.55

APLPPQPRK

16.12

-3.85

-4.52

P39732

RSPSVSPVR

12.99

-2.61

-3.28

RHPSIAPPS

14.74

-2.06

-2.73

P40091

PSHPHHNSR

15.15

-2.65

-3.32

P40450

PKLFPRLSS

11.65

-3.28

-3.95

PPPLPQSLL

13.24

-4.53

-5.20

LVTPPAPPL

13.77

-3.97

-4.64

P32917

RFPPYSPLL

11.01

-4.31

-4.98

IPPKVAPFG

13.99

-2.04

-2.71

LPQHPHRTS

15.03

-2.75

-3.42

P25376

DRPSSQPHL

12.68

-2.72

-3.39

P40020

LPPLPFPLY

10.23

-4.75

-5.42

LYLTPESPL

12.53

-2.82

-3.49

PPLTPEKNL

13.47

-3.16

-3.83

P41832

PPPPPMALF

14.67

-4.22

-4.89

PPPLPSVLS

14.76

-2.21

-2.88

PPPPMALFG

16.16

-3.48

-4.15

Q12114

KSEPVGTPN

16.20

-0.77

-1.44

Q03466

VPMAPDTFN

14.97

-0.48

-1.15

P53046

LSTPPTPKS

14.05

-3.30

-3.97

PPTPKSAGH

15.58

-1.97

-2.64

TPPTPKSAG

16.10

-0.43

-1.10

P53947

FNPIQDPFT

14.02

-1.76

-2.43

Q12753

IKPKGRPST

11.11

-4.16

-4.83

PRMPKTGSR

11.91

-2.82

-3.49

MIKPKGRPS

11.98

-3.41

-4.08

P34250

PKEPPARKS

14.62

-2.58

-3.25

YPKEPPARK

15.35

-6.02

-6.69

P53950

APLLPLPSL

13.55

-4.21

-4.88

SNPNGAPLR

13.63

-1.03

-1.70

PNGAPLRRY

14.33

-3.63

-4.30

P40210

DPTEPQTND

15.81

-2.30

-2.97

 


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