ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1SHF-2.PDB
Scoring matrix: FUS1_1SHF-2_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 26.59
Foldx random average score for Saccharomyces cerevisiae: 21.186

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3199860
Proteins after random average filtering: 7178
 Total fragments: 1274440
Proteins after disorder filtering: 4270
 Total fragments: 57932
Proteins after pattern filtering: 2048
 Total fragments: 10826
Proteins after MINT filtering: 21
 Total fragments: 141


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

26.59

-0.20

0.00

Best peptides

HKWHRWEKRR

0.00

2.74

2.95

         
Interactors      
Q12280

VTPPLRPQSS

18.08

-1.69

-1.48

TAPASPEEPK

18.51

-4.03

-3.83

GTNVTPPLRP

18.53

-7.13

-6.92

P31374

RKTKPPPPLD

16.33

-4.97

-4.76

NISPERPSFR

16.37

-4.37

-4.17

NNISPERPSF

16.43

-4.45

-4.25

P36119

TRPTVQPSNQ

19.61

-3.43

-3.23

SSTTRPTVQP

20.79

-2.55

-2.34

P40073

QFDGYPQQQP

17.96

-4.42

-4.21

P24583

ANAPLPPQPR

16.24

-3.52

-3.31

RANAPLPPQP

18.19

-7.24

-7.04

NAPLPPQPRK

18.35

-3.81

-3.61

P39732

RHPSIAPPSK

17.71

-5.47

-5.26

RSPSVSPVRT

18.33

-4.05

-3.84

STRHPSIAPP

19.30

-3.41

-3.21

P21268

LNLSKPISPP

15.91

-4.12

-3.92

SKPISPPPSL

18.28

-3.85

-3.65

LSKPISPPPS

19.39

-3.54

-3.34

P40091

QNPSHPHHNS

16.94

-3.23

-3.02

PSHPHHNSRP

18.02

-6.10

-5.89

NPSHPHHNSR

18.92

-6.64

-6.43

P40450

VSSSPKLFPR

14.95

-4.65

-4.45

QLPPPPPPPP

16.58

-7.15

-6.95

PKLFPRLSSD

17.15

-1.19

-0.98

P32917

QSRFPPYSPL

15.99

-2.63

-2.42

DYLPQHPHRT

16.95

-4.48

-4.28

DNIPPKVAPF

17.27

-0.97

-0.77

P25376

SNDRPSSQPH

20.81

-3.02

-2.81

P40020

ISLPPYLSPQ

15.95

-3.87

-3.67

NLYLTPESPL

16.55

-5.79

-5.59

YLTPESPLNR

17.85

-4.05

-3.84

P41832

LSSQPPPPPP

16.63

-5.36

-5.16

PKGETPPPPP

18.00

-6.28

-6.08

VLSSQPPPPP

18.92

-6.07

-5.87

P16892

QTYHDPNDEP

16.84

-5.45

-5.25

YHDPNDEPEG

19.66

-1.13

-0.92

Q03466

SSVPMAPDTF

20.89

-3.56

-3.36

GSSVPMAPDT

21.00

-4.61

-4.41

P14681

YHDPSDEPEY

17.80

-2.89

-2.69

P53046

QLSTPPTPKS

17.89

-3.81

-3.61

NQLSTPPTPK

19.21

-6.15

-5.95

P53947

ASPFNPIQDP

20.38

-5.94

-5.74

FNPIQDPFTD

20.81

-3.02

-2.81

Q12753

IKPKGRPSTT

14.45

-4.35

-4.14

QSINSPRMPK

14.69

-3.41

-3.21

INSPRMPKTG

15.12

-4.32

-4.12

P34250

LYPKEPPARK

14.13

-6.42

-6.21

PYHSKKPSNP

17.13

-7.15

-6.95

YHSKKPSNPP

17.75

-5.87

-5.67

P53950

SNPNGAPLRR

16.24

-5.79

-5.59

PNGAPLRRYS

18.92

-8.21

-8.01

NTPPAPLLPL

20.00

-3.52

-3.31

 


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