ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1SHF-19.PDB
Scoring matrix: FUS1_1SHF-19_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 17.41
Foldx random average score for Saccharomyces cerevisiae: 16.922

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3207038
Proteins after random average filtering: 7178
 Total fragments: 1420859
Proteins after disorder filtering: 4559
 Total fragments: 75810
Proteins after pattern filtering: 2058
 Total fragments: 8446
Proteins after MINT filtering: 21
 Total fragments: 93


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

17.41

-0.73

0.00

Best peptides

FRSRYGRSG

0.00

0.76

1.49

         
Interactors      
Q12280

PPLRPQSSS

13.04

-2.47

-1.74

NVTPPLRPQ

14.13

-2.03

-1.30

PLRPQSSSK

14.78

-2.25

-1.52

P36119

TRPTVQPSN

16.24

0.21

0.94

P53046

PPTPKSAGH

15.78

-2.20

-1.47

LSTPPTPKS

16.46

-2.93

-2.20

P40073

GYPQQQPSH

14.17

-1.55

-0.82

FDGYPQQQP

16.14

-4.98

-4.25

P24583

APLPPQPRK

12.65

-3.44

-2.71

LPPQPRKHD

12.68

-3.17

-2.44

PPQPRKHDK

15.59

-1.99

-1.26

P39732

ASSSPSPSP

15.76

-1.95

-1.22

RSPSVSPVR

16.01

-0.86

-0.13

P21268

KPISPPPSL

16.30

-2.66

-1.93

P40091

NPSHPHHNS

12.10

-1.32

-0.59

DPSSPSSVG

14.29

0.70

1.43

GMSSPASSP

14.74

-0.83

-0.10

P40450

PPLPESLSM

13.70

-4.02

-3.29

PPAPPLPNG

13.71

-3.33

-2.60

PKLFPRLSS

14.42

-3.61

-2.88

P32917

RFPPYSPLL

10.53

-2.63

-1.90

LPQHPHRTS

13.92

-2.00

-1.27

DYLPQHPHR

13.95

-2.78

-2.05

P25376

PSSQPHLGY

13.28

-0.53

0.20

DRPSSQPHL

13.85

-1.11

-0.38

P40020

ISLPPYLSP

12.76

-3.85

-3.12

RVLPPLPFP

14.07

-3.93

-3.20

PPLTPEKNL

14.43

-2.96

-2.23

P41832

PPPPMALFG

13.59

-2.86

-2.13

PPPPPLPSV

15.40

-3.07

-2.34

GVIPPAPPM

15.78

-4.01

-3.28

P16892

NDEPEGEPI

15.39

-2.41

-1.68

Q03466

VPMAPDTFN

15.91

-1.19

-0.46

Q12114

KSEPVGTPN

15.04

-0.56

0.17

LKSEPVGTP

16.41

-3.86

-3.13

P31374

NISPERPSF

11.43

-1.70

-0.97

FEQPRLPST

11.55

-2.85

-2.12

NKKPGTPVF

14.10

-1.64

-0.91

Q12753

MIKPKGRPS

10.79

-3.40

-2.67

PRMPKTGSR

11.35

-3.59

-2.86

MMIKPKGRP

13.39

-9.19

-8.46

P34250

PKEPPARKS

14.43

-2.75

-2.02

ALYPKEPPA

15.58

-1.58

-0.85

KPSNPPSSG

16.22

-2.83

-2.10

P53950

NPSIPSAST

15.06

-0.90

-0.17

KTAPSTAPL

15.35

-1.12

-0.39

PNGAPLRRY

15.47

-2.07

-1.34

P40210

DPTEPQTND

15.92

1.09

1.82

 


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