ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1SHF-18.PDB
Scoring matrix: FUS1_1SHF-18_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAAA
Foldx wt ligand score: 19.63
Foldx random average score for Saccharomyces cerevisiae: 16.432

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3199860
Proteins after random average filtering: 7178
 Total fragments: 1442005
Proteins after disorder filtering: 4518
 Total fragments: 84204
Proteins after pattern filtering: 2212
 Total fragments: 13390
Proteins after MINT filtering: 23
 Total fragments: 178


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAAA

19.63

4.37

0.00

Best peptides

RSPWPPIQWR

0.00

7.07

2.70

         
Interactors      
P36119

STTRPTVQPS

11.61

0.39

-3.98

RPTVQPSNQS

12.04

0.40

-3.97

PTVQPSNQST

12.97

2.47

-1.90

P53950

NPNGAPLRRY

12.38

-1.51

-5.88

SNPNGAPLRR

13.52

-0.68

-5.05

NTPPAPLLPL

13.76

0.13

-4.24

P40073

FDGYPQQQPS

12.29

-1.35

-5.72

GYPQQQPSHT

15.21

-1.73

-6.10

P24583

ANAPLPPQPR

10.45

-0.11

-4.48

LPPQPRKHDK

12.53

-4.16

-8.53

PLPPQPRKHD

12.54

-2.13

-6.50

P53947

ASPFNPIQDP

13.71

3.00

-1.37

SPFNPIQDPF

16.07

0.28

-4.09

P34250

LYPKEPPARK

10.43

-1.31

-5.68

HSKKPSNPPS

11.45

-1.75

-6.12

YPKEPPARKS

11.84

-3.41

-7.78

P53046

NQLSTPPTPK

13.79

0.01

-4.36

TPPTPKSAGH

14.04

-1.79

-6.16

LSTPPTPKSA

14.55

0.93

-3.44

Q12280

TNVTPPLRPQ

11.10

-3.16

-7.53

AYSGSPSKPG

13.59

-0.64

-5.01

SPSKPGNNNS

13.91

-0.62

-4.99

P39732

RSPSVSPVRT

11.00

-0.16

-4.53

HPSIAPPSKL

12.17

-0.76

-5.13

SSRSPSVSPV

13.20

1.28

-3.09

P40091

SPASSPVTWD

13.43

-0.26

-4.63

NPSHPHHNSR

13.88

-0.48

-4.85

QNPSHPHHNS

14.11

-0.51

-4.88

P40450

VSSSPKLFPR

11.21

-0.34

-4.71

APPPLPDLFK

12.51

-3.51

-7.88

SPKLFPRLSS

12.83

-2.87

-7.24

P25376

RPSSQPHLGY

8.05

-3.82

-8.19

SNDRPSSQPH

10.63

-2.28

-6.65

P41832

IPPAPPMMPA

11.35

-3.12

-7.49

ETPPPPPLPS

13.14

0.42

-3.95

PPPLPSVLSS

13.19

-0.62

-4.99

Q03466

SVPMAPDTFN

14.11

-2.76

-7.13

P31374

LSNKKPGTPV

10.53

0.90

-3.47

GNNISPERPS

10.56

-2.33

-6.70

ISPERPSFRQ

11.33

-1.58

-5.95

P32917

YSPLLPPFGL

9.01

-2.92

-7.29

STDYLPQHPH

9.86

-4.17

-8.54

QSRFPPYSPL

10.98

-1.59

-5.96

P40020

LPPYLSPQNK

7.77

-4.87

-9.24

KSRVLPPLPF

8.37

-1.04

-5.41

LPPLPFPLYD

11.44

-5.99

-10.36

P16892

EPEGEPIPPS

16.11

-0.48

-4.85

P40210

HDEVDPTEPQ

16.04

0.16

-4.21

Q12114

GHETAPVSPV

12.63

0.49

-3.88

LKSEPVGTPN

15.32

-0.53

-4.90

P21268

PISPPPSLKK

13.73

0.23

-4.14

SKPISPPPSL

14.63

0.32

-4.05

LSKPISPPPS

14.69

-0.43

-4.80

Q12753

QSINSPRMPK

9.72

-1.30

-5.67

MMIKPKGRPS

10.17

-3.85

-8.22

RNDLPDTSPM

11.16

-2.03

-6.40

P14681

DEPEYPPLNL

14.95

-1.48

-5.85

PSDEPEYPPL

16.12

0.41

-3.96

 


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