ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1SHF-17.PDB
Scoring matrix: FUS1_1SHF-17_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 19.44
Foldx random average score for Saccharomyces cerevisiae: 18.249

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3207038
Proteins after random average filtering: 7178
 Total fragments: 1517591
Proteins after disorder filtering: 4530
 Total fragments: 73517
Proteins after pattern filtering: 1968
 Total fragments: 7185
Proteins after MINT filtering: 18
 Total fragments: 89


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

19.44

-0.90

0.00

Best peptides

RRKFYGMWR

0.00

-3.10

-2.20

         
Interactors      
Q12280

PPLRPQSSS

14.96

-1.59

-0.69

SPSKPGNNN

15.98

-3.65

-2.75

PLRPQSSSK

16.46

-2.00

-1.10

P31374

NISPERPSF

13.55

-3.24

-2.34

SPERPSFRQ

14.28

-4.83

-3.93

PRLPSTASS

15.53

-0.74

0.16

P36119

TRPTVQPSN

13.17

-0.88

0.02

P40073

GYPQQQPSH

14.99

-2.76

-1.86

P24583

APLPPQPRK

13.91

-6.97

-6.07

LPPQPRKHD

14.57

-3.52

-2.62

RANAPLPPQ

15.45

-4.28

-3.38

P39732

RSPSVSPVR

15.31

-3.15

-2.25

RHPSIAPPS

17.03

-1.40

-0.50

PSPSPTSSA

17.76

-0.18

0.72

P40091

PSHPHHNSR

14.98

-1.38

-0.48

NPSHPHHNS

17.13

-3.44

-2.54

SQNPSHPHH

17.50

-2.05

-1.15

P40450

PKLFPRLSS

11.13

-3.06

-2.16

LVTPPAPPL

14.69

-5.06

-4.16

SSPKLFPRL

14.84

-4.52

-3.62

P32917

RFPPYSPLL

11.15

-4.34

-3.44

LPQHPHRTS

13.59

-2.68

-1.78

DYLPQHPHR

14.67

-4.34

-3.44

P25376

PSSQPHLGY

15.06

-0.86

0.04

DRPSSQPHL

15.26

-2.93

-2.03

P40020

LPPLPFPLY

12.55

-4.76

-3.86

LYLTPESPL

14.37

-2.30

-1.40

PPLTPEKNL

14.65

-2.83

-1.93

P41832

PPPPPMALF

15.97

-3.48

-2.58

GVIPPAPPM

16.44

-3.71

-2.81

PPPPPVPAK

18.04

-3.18

-2.28

Q12114

KSEPVGTPN

18.13

-0.55

0.35

Q03466

VPMAPDTFN

16.84

-0.35

0.55

P53046

LSTPPTPKS

15.68

-3.07

-2.17

PPTPKSAGH

16.93

-2.09

-1.19

TPPTPKSAG

17.54

-0.56

0.34

Q12753

PRMPKTGSR

10.53

-3.26

-2.36

MIKPKGRPS

14.56

-2.80

-1.90

IKPKGRPST

14.58

-3.98

-3.08

P34250

PKEPPARKS

16.62

-1.75

-0.85

P53950

APLLPLPSL

12.72

-4.13

-3.23

PNGAPLRRY

15.88

-5.06

-4.16

DSNPNGAPL

15.95

-0.28

0.62

 


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