ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1SHF-13.PDB
Scoring matrix: FUS1_1SHF-13_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 17.24
Foldx random average score for Saccharomyces cerevisiae: 12.694

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3214216
Proteins after random average filtering: 7178
 Total fragments: 1334043
Proteins after disorder filtering: 4168
 Total fragments: 49517
Proteins after pattern filtering: 1793
 Total fragments: 7288
Proteins after MINT filtering: 18
 Total fragments: 92


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

17.24

-1.11

0.00

Best peptides

RRPRRRWR

0.00

-2.33

-1.23

         
Interactors      
Q12280

TPPLRPQS

9.51

-5.12

-4.02

NVTPPLRP

11.75

-4.64

-3.53

PPLRPQSS

12.17

-3.12

-2.02

P31374

SPERPSFR

6.59

-5.98

-4.88

RKTKPPPP

9.77

-4.12

-3.02

PDDLPPLK

10.45

-6.81

-5.71

P36119

RPTVQPSN

11.46

-3.14

-2.04

P24583

LPPQPRKH

10.03

-4.75

-3.65

PLPPQPRK

11.23

-5.00

-3.90

NAPLPPQP

11.48

-3.73

-2.63

P39732

SPSVSPVR

10.46

-2.67

-1.56

RHPSIAPP

10.61

-3.12

-2.02

SRSPSVSP

12.59

-1.84

-0.74

P21268

SKPISPPP

12.46

-1.71

-0.60

P40091

QNPSHPHH

12.12

-2.70

-1.60

P40450

SPKLFPRL

8.80

-5.85

-4.74

PKLFPRLS

9.38

-6.29

-5.19

PPPLPDLF

10.25

-6.56

-5.46

P32917

YLPQHPHR

8.37

-5.69

-4.59

FPPYSPLL

9.38

-4.25

-3.15

SPLLPPFG

9.44

-6.71

-5.61

P25376

RPSSQPHL

10.69

-5.25

-4.14

P40020

SRVLPPLP

7.71

-6.72

-5.62

PPLPFPLY

10.17

-4.92

-3.81

PLPFPLYD

10.44

-5.30

-4.20

P41832

PPPVPAKL

11.21

-3.72

-2.62

TPPPPPLP

11.25

-4.75

-3.65

PPPLPSVL

11.34

-5.18

-4.07

P53947

ASPFNPIQ

10.55

-4.65

-3.55

P34250

PKEPPARK

10.67

-5.36

-4.26

YPKEPPAR

10.81

-2.99

-1.89

P14681

EPEYPPLN

11.09

-5.83

-4.72

Q12753

NSPRMPKT

9.56

-4.27

-3.16

MIKPKGRP

10.35

-4.64

-3.53

SINSPRMP

11.25

-4.57

-3.47

P53046

STPPTPKS

11.78

-1.19

-0.08

P53950

PNGAPLRR

9.84

-3.26

-2.15

PAPLLPLP

10.12

-5.08

-3.98

TPPAPLLP

11.59

-4.15

-3.05

 


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