ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1SHF-12.PDB
Scoring matrix: FUS1_1SHF-12_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 11.47
Foldx random average score for Saccharomyces cerevisiae: 9.682

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3214216
Proteins after random average filtering: 7178
 Total fragments: 1271734
Proteins after disorder filtering: 4482
 Total fragments: 74400
Proteins after pattern filtering: 2181
 Total fragments: 13391
Proteins after MINT filtering: 21
 Total fragments: 200


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

11.47

-0.35

0.00

Best peptides

KWWKRYWK

0.00

0.69

1.04

         
Interactors      
Q12280

VTPPLRPQ

5.69

-3.79

-3.44

PSKPGNNN

6.40

-2.45

-2.10

NVTPPLRP

7.45

-3.51

-3.16

P31374

PERPSFRQ

6.02

-3.86

-3.51

FEQPRLPS

6.06

-3.26

-2.91

KTKPPPPL

6.61

-2.20

-1.85

P36119

TRPTVQPS

8.37

-2.56

-2.21

TTRPTVQP

8.62

-2.62

-2.27

P40073

DGYPQQQP

6.76

-3.48

-3.13

GYPQQQPS

8.98

-2.02

-1.67

P24583

APLPPQPR

6.59

-5.04

-4.69

PPQPRKHD

7.24

-3.73

-3.38

PLPPQPRK

7.52

-3.28

-2.93

P39732

TRHPSIAP

7.75

-3.22

-2.87

SSPSPSPT

9.00

-1.04

-0.69

RHPSIAPP

9.26

-1.62

-1.27

P21268

NLSKPISP

7.92

-2.44

-2.09

LSKPISPP

8.27

-2.20

-1.85

SKPISPPP

8.37

-2.09

-1.74

P40091

PSHPHHNS

6.59

-3.20

-2.85

QNPSHPHH

8.64

-2.50

-2.15

SQNPSHPH

8.65

-1.94

-1.59

P40450

SSPKLFPR

5.14

-2.61

-2.26

PAPPPLPD

6.66

-3.71

-3.36

AVPPPPPP

6.98

-2.99

-2.64

P32917

SRFPPYSP

4.80

-4.86

-4.51

TDYLPQHP

6.06

-3.99

-3.64

PQHPHRTS

7.08

-4.02

-3.67

P25376

DRPSSQPH

7.44

-3.01

-2.66

NDRPSSQP

8.63

-1.79

-1.44

P40020

RVLPPLPF

5.83

-5.24

-4.89

PYLSPQNK

6.15

-2.46

-2.11

DRPPPLTP

6.84

-4.83

-4.48

P41832

SSQPPPPP

6.69

-2.12

-1.77

ETPPPPPL

7.05

-3.02

-2.67

SQPPPPPP

7.23

-3.08

-2.73

P16892

GEPIPPSF

8.81

-2.21

-1.86

Q03466

SVPMAPDT

8.80

-1.18

-0.83

P14681

PEYPPLNL

4.34

-4.81

-4.46

SDEPEYPP

7.45

-2.07

-1.72

P53046

STPPTPKS

8.08

-3.09

-2.74

TPPTPKSA

8.98

-2.60

-2.25

LSTPPTPK

9.04

-1.44

-1.09

P53947

PIQDPFTD

9.19

-1.31

-0.96

SPFNPIQD

9.22

-2.89

-2.54

ASPFNPIQ

9.39

-1.62

-1.27

Q12753

IKPKGRPS

5.11

-3.57

-3.22

HRYPPMAP

5.57

-4.62

-4.27

SPRMPKTG

7.04

-3.35

-3.00

P34250

HSKKPSNP

6.09

-2.31

-1.96

EPKPAYVP

6.98

-3.70

-3.35

SKKPSNPP

7.01

-2.62

-2.27

P53950

APLLPLPS

7.79

-5.16

-4.81

NTPPAPLL

8.15

-2.51

-2.16

PLLPLPSL

8.67

-0.02

0.33

 


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