ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1PWT-9.PDB
Scoring matrix: FUS1_1PWT-9_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 16.33
Foldx random average score for Saccharomyces cerevisiae: 12.180

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3214216
Proteins after random average filtering: 7178
 Total fragments: 1358250
Proteins after disorder filtering: 4404
 Total fragments: 56038
Proteins after pattern filtering: 2024
 Total fragments: 9946
Proteins after MINT filtering: 21
 Total fragments: 170


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

16.33

0.00

0.00

Best peptides

RRYMYPRR

0.00

-3.98

-3.98

         
Interactors      
Q12280

NVTPPLRP

9.78

-3.96

-3.96

TPPLRPQS

10.13

-2.95

-2.95

YSGSPSKP

11.19

-1.42

-1.42

P36119

RPTVQPSN

9.96

-3.11

-3.11

P53046

STPPTPKS

11.89

-1.46

-1.46

TPPTPKSA

11.93

-0.57

-0.57

QLSTPPTP

11.95

-1.94

-1.94

P24583

LPPQPRKH

10.13

-3.41

-3.41

RANAPLPP

10.59

-1.61

-1.61

NAPLPPQP

10.69

-3.08

-3.08

P39732

RHPSIAPP

9.62

-1.84

-1.84

PSVSPVRT

10.59

-2.25

-2.25

SPSVSPVR

10.76

-3.23

-3.23

P21268

SKPISPPP

10.31

-4.18

-4.18

NLSKPISP

11.31

-2.20

-2.20

KPISPPPS

11.45

-2.86

-2.86

P40091

NPSHPHHN

12.05

-2.88

-2.88

VTWDPSSP

12.09

-1.18

-1.18

P40450

SPKLFPRL

7.95

-5.46

-5.46

PPPLPDLF

8.09

-4.39

-4.39

PKLFPRLS

8.14

-4.44

-4.44

P32917

YSPLLPPF

9.30

-3.01

-3.01

SPLLPPFG

9.32

-4.17

-4.17

RFPPYSPL

9.38

-2.58

-2.58

P25376

RPSSQPHL

10.35

-2.12

-2.12

PSSQPHLG

11.44

-1.35

-1.35

P40020

SRVLPPLP

7.04

-4.97

-4.97

RVLPPLPF

8.91

-2.48

-2.48

PLPFPLYD

9.66

-4.72

-4.72

P41832

PPPVPAKL

9.44

-4.14

-4.14

TPPPPPLP

10.09

-2.21

-2.21

IPPAPPMM

10.12

-3.92

-3.92

P16892

GEPIPPSF

10.68

-3.96

-3.96

Q03466

GSSVPMAP

10.96

-2.09

-2.09

SVPMAPDT

11.81

-3.55

-3.55

Q12114

PVGTPNIE

12.16

-2.69

-2.69

P31374

RKTKPPPP

6.41

-3.39

-3.39

SPERPSFR

7.99

-4.56

-4.56

KPGTPVFP

9.24

-3.99

-3.99

P53947

ASPFNPIQ

9.63

-2.72

-2.72

FNPIQDPF

10.11

-2.16

-2.16

Q12753

MIKPKGRP

7.82

-4.55

-4.55

NSPRMPKT

10.14

-3.12

-3.12

SINSPRMP

10.51

-4.58

-4.58

P34250

YPKEPPAR

9.54

-3.64

-3.64

PKEPPARK

9.63

-4.10

-4.10

ESSNPDLP

10.36

-1.79

-1.79

P14681

EPEYPPLN

9.48

-4.88

-4.88

PSDEPEYP

10.74

-1.32

-1.32

DEPEYPPL

12.10

-2.13

-2.13

P53950

PNGAPLRR

8.80

-5.04

-5.04

PAPLLPLP

10.20

-3.88

-3.88

TPPAPLLP

10.27

-2.77

-2.77

 


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