ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1PWT-8.PDB
Scoring matrix: FUS1_1PWT-8_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 12.05
Foldx random average score for Saccharomyces cerevisiae: 9.153

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3214216
Proteins after random average filtering: 7178
 Total fragments: 1361947
Proteins after disorder filtering: 4428
 Total fragments: 66244
Proteins after pattern filtering: 2137
 Total fragments: 11319
Proteins after MINT filtering: 22
 Total fragments: 163


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

12.05

0.34

0.00

Best peptides

RMRPRWPF

0.00

-2.73

-3.07

         
Interactors      
P36119

TTRPTVQP

8.53

-2.08

-2.42

TRPTVQPS

8.54

-3.48

-3.82

P53950

PNPSIPSA

6.68

-3.14

-3.48

PPAPLLPL

7.50

-2.42

-2.76

PLLPLPSL

7.51

-3.08

-3.42

P40073

YPQQQPSH

8.91

-0.61

-0.95

P24583

ANAPLPPQ

6.75

-1.39

-1.73

PPQPRKHD

6.81

-2.11

-2.45

PLPPQPRK

7.33

-3.48

-3.82

P53947

ASPFNPIQ

7.39

-2.01

-2.35

FNPIQDPF

7.39

-0.85

-1.19

PFNPIQDP

7.74

-3.24

-3.58

P34250

SKKPSNPP

6.90

-1.88

-2.22

YPKEPPAR

7.40

-2.42

-2.76

PKPAYVPP

7.41

-2.82

-3.16

P53046

TPPTPKSA

8.58

-2.10

-2.44

STPPTPKS

9.13

-0.51

-0.85

Q12280

VTPPLRPQ

6.26

-3.37

-3.71

TPPLRPQS

7.34

-1.62

-1.96

GSPSKPGN

8.23

-1.91

-2.25

P39732

RHPSIAPP

7.53

-4.19

-4.53

PSIAPPSK

8.78

-2.19

-2.53

TRHPSIAP

8.99

-2.15

-2.49

P40091

QNPSHPHH

7.87

-1.61

-1.95

P40450

SPKLFPRL

6.01

-1.97

-2.31

APPPLPDL

6.44

-2.77

-3.11

SSPKLFPR

6.51

-3.68

-4.02

P25376

DRPSSQPH

8.23

-1.73

-2.07

P41832

PPPPMALF

6.14

-3.63

-3.97

PPPPVPAK

6.46

-4.01

-4.35

VIPPAPPM

6.76

-2.70

-3.04

Q03466

PMAPDTFN

8.54

-1.30

-1.64

P31374

ISPERPSF

4.93

-2.61

-2.95

PERPSFRQ

6.19

-2.91

-3.25

FEQPRLPS

6.52

-1.01

-1.35

P32917

YSPLLPPF

5.87

-3.06

-3.40

RFPPYSPL

6.87

-1.61

-1.95

IPPKVAPF

6.91

-4.11

-4.45

P40020

PPLPFPLY

5.85

-2.56

-2.90

VNPHSIPF

6.50

-2.74

-3.08

SLPPYLSP

6.88

-3.14

-3.48

P16892

GEPIPPSF

7.15

-2.71

-3.05

EGEPIPPS

8.91

-1.19

-1.53

Q12114

EPVGTPNI

8.71

-0.81

-1.15

P21268

SKPISPPP

7.77

-2.16

-2.50

LSKPISPP

8.00

-2.30

-2.64

KPISPPPS

9.03

-1.85

-2.19

Q12753

INSPRMPK

5.79

-2.64

-2.98

KPKGRPST

6.46

-1.88

-2.22

SPRMPKTG

7.59

-2.34

-2.68

P14681

DEPEYPPL

6.72

-1.65

-1.99

DPSDEPEY

8.64

-1.61

-1.95

 


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