ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1PWT-29.PDB
Scoring matrix: FUS1_1PWT-29_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 17.36
Foldx random average score for Saccharomyces cerevisiae: 12.248

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3199860
Proteins after random average filtering: 7178
 Total fragments: 1412489
Proteins after disorder filtering: 4058
 Total fragments: 48614
Proteins after pattern filtering: 2028
 Total fragments: 10644
Proteins after MINT filtering: 20
 Total fragments: 148


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

17.36

-2.29

0.00

Best peptides

RWRPWKPNMW

0.00

-4.80

-2.51

         
Interactors      
Q12280

PLRPQSSSKI

10.46

-6.14

-3.85

AYSGSPSKPG

10.65

-4.87

-2.59

GTNVTPPLRP

10.99

-5.67

-3.38

P36119

RPTVQPSNQS

10.53

-6.19

-3.91

SSTTRPTVQP

11.83

-7.11

-4.83

P53046

NQLSTPPTPK

10.11

-7.65

-5.37

QLSTPPTPKS

12.14

-5.78

-3.50

P24583

PLPPQPRKHD

9.90

-6.50

-4.21

PPQPRKHDKT

10.88

-3.94

-1.65

APLPPQPRKH

11.24

-5.63

-3.34

P39732

TRHPSIAPPS

10.48

-4.98

-2.70

RHPSIAPPSK

10.98

-5.79

-3.50

PSIAPPSKLN

11.32

-5.38

-3.09

P21268

PLNLSKPISP

9.19

-5.36

-3.08

PISPPPSLKK

10.00

-5.89

-3.60

LSKPISPPPS

10.55

-6.08

-3.79

P53950

NPNGAPLRRY

9.94

-5.74

-3.46

VVAPNPSIPS

10.78

-7.11

-4.83

NTPPAPLLPL

10.82

-6.67

-4.38

P40450

SPKLFPRLSS

8.98

-7.74

-5.46

PPPPPPPLPQ

10.14

-7.23

-4.95

DLVTPPAPPL

10.24

-7.11

-4.83

P32917

NIPPKVAPFG

9.48

-5.65

-3.37

DNIPPKVAPF

10.17

-6.65

-4.37

DYLPQHPHRT

10.32

-6.46

-4.17

P25376

DRPSSQPHLG

11.50

-8.12

-5.83

GSNDRPSSQP

11.82

-6.92

-4.63

P40020

PLTPEKNLYL

8.53

-6.28

-4.00

SLPPYLSPQN

9.88

-5.36

-3.08

KSRVLPPLPF

10.04

-9.06

-6.78

P41832

VIPPAPPMMP

9.09

-8.47

-6.19

PPPPPMALFG

10.50

-7.41

-5.13

ETPPPPPLPS

10.54

-7.18

-4.89

P16892

TYHDPNDEPE

11.62

-4.27

-1.98

Q03466

SVPMAPDTFN

10.65

-6.52

-4.23

PMAPDTFNVK

11.32

-6.02

-3.73

Q12114

SEPVGTPNIE

11.68

-4.85

-2.56

LKSEPVGTPN

11.88

-4.28

-2.00

SLKSEPVGTP

11.97

-5.83

-3.54

P31374

FRKTKPPPPL

8.47

-7.71

-5.42

SFRKTKPPPP

8.73

-7.16

-4.88

PERPSFRQPF

8.95

-4.66

-2.38

P53947

PFNPIQDPFT

10.36

-4.80

-2.51

NPIQDPFTDN

12.21

-4.88

-2.59

Q12753

MMIKPKGRPS

7.38

-8.16

-5.88

KPKGRPSTTC

9.13

-8.55

-6.27

NHRYPPMAPT

9.91

-6.10

-3.81

P34250

YPKEPPARKS

9.24

-5.99

-3.71

YHSKKPSNPP

9.40

-6.31

-4.02

LYPKEPPARK

9.66

-7.06

-4.77

P14681

DEPEYPPLNL

10.36

-8.27

-5.98

EPEYPPLNLD

11.54

-5.48

-3.20

 


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