ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1PWT-28.PDB
Scoring matrix: FUS1_1PWT-28_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 18.23
Foldx random average score for Saccharomyces cerevisiae: 14.743

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3199860
Proteins after random average filtering: 7177
 Total fragments: 1773112
Proteins after disorder filtering: 4478
 Total fragments: 84062
Proteins after pattern filtering: 2091
 Total fragments: 10786
Proteins after MINT filtering: 21
 Total fragments: 150


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

18.23

-0.91

0.00

Best peptides

RKPRYPTRYC

0.00

-5.00

-4.09

         
Interactors      
Q12280

PPLRPQSSSK

11.01

-5.30

-4.39

SPSKPGNNNS

12.49

-3.36

-2.45

TPPLRPQSSS

12.78

-4.62

-3.71

P36119

RPTVQPSNQS

11.07

-7.30

-6.39

TRPTVQPSNQ

14.23

-4.20

-3.29

P53046

QLSTPPTPKS

9.50

-4.93

-4.02

STPPTPKSAG

12.85

-4.62

-3.71

TPPTPKSAGH

12.97

-2.76

-1.85

P24583

NAPLPPQPRK

12.28

-5.75

-4.84

LPPQPRKHDK

12.78

-7.12

-6.21

APLPPQPRKH

13.31

-5.54

-4.63

P39732

SRSPSVSPVR

11.69

-3.58

-2.67

RHPSIAPPSK

12.10

-5.63

-4.72

HPSIAPPSKL

12.12

-6.00

-5.09

P21268

PISPPPSLKK

11.65

-5.96

-5.05

KPISPPPSLK

12.29

-4.70

-3.79

SKPISPPPSL

12.41

-5.14

-4.23

P40091

WDPSSPSSVG

11.89

-5.45

-4.54

QNPSHPHHNS

12.85

-5.07

-4.16

DPSSPSSVGS

13.61

-2.77

-1.86

P40450

TPPAPPLPNG

10.32

-6.06

-5.15

PPPPPPLPQS

10.98

-5.04

-4.13

PPPPPPLPES

11.31

-5.08

-4.17

P32917

SPLLPPFGLS

10.37

-6.48

-5.57

PQHPHRTSSL

10.57

-6.16

-5.25

SRFPPYSPLL

10.88

-5.50

-4.59

P25376

DRPSSQPHLG

12.20

-4.56

-3.65

P40020

PHSIPFSVLS

9.21

-5.41

-4.50

DRPPPLTPEK

9.87

-6.07

-5.16

SLPPYLSPQN

11.32

-5.61

-4.70

P41832

PPPPLPSVLS

10.21

-5.02

-4.11

PPPPPPMALF

11.25

-6.62

-5.71

TPPPPPLPSV

12.13

-6.12

-5.21

P16892

YHDPNDEPEG

11.82

-3.85

-2.94

PEGEPIPPSF

14.74

-4.17

-3.26

Q03466

VPMAPDTFNV

11.54

-3.85

-2.94

PMAPDTFNVK

14.13

-7.39

-6.48

Q12114

KSEPVGTPNI

11.80

-4.67

-3.76

P31374

EQPRLPSTAS

10.12

-3.26

-2.35

QPRLPSTASS

10.68

-3.17

-2.26

SNKKPGTPVF

11.57

-4.96

-4.05

Q12753

SPRMPKTGSR

9.66

-4.64

-3.73

KPKGRPSTTC

10.09

-5.76

-4.85

YPPMAPTTVA

10.61

-5.27

-4.36

P34250

KKPSNPPSSG

10.85

-5.63

-4.72

YPKEPPARKS

11.28

-5.83

-4.92

PKPAYVPPED

13.25

-5.07

-4.16

P14681

EPEYPPLNLD

12.27

-4.31

-3.40

DEPEYPPLNL

12.67

-5.64

-4.73

P53950

PNGAPLRRYS

11.97

-4.27

-3.36

PAPLLPLPSL

12.79

-5.93

-5.02

NPSIPSASTS

13.11

-5.12

-4.21

P40210

DPTEPQTNDS

11.25

-3.54

-2.63

 


    Comments or questions on the site? Send a mail to adandatabase@umh.es                                                     
DISCLAIMER