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Matrix information:
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ADAN-name: FUS1_1PWT-26.PDB
Scoring matrix: FUS1_1PWT-26_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 18.32
Foldx random average score for Saccharomyces cerevisiae: 12.966 Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
Proteins belonging to other specie: 0
Nš of interactions described: 47
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
Total fragments: 3207038
Proteins after random average filtering: 7178
Total fragments: 1369071
Proteins after disorder filtering: 4240
Total fragments: 56154
Proteins after pattern filtering: 2024
Total fragments: 10500
Proteins after MINT filtering: 21
Total fragments: 156
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAAAA |
18.32
|
0.78 |
0.00 |
| Best peptides |
YRFKKFRPF |
0.00
|
-3.49 |
-4.27 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| Q12280 |
NVTPPLRPQ |
9.86
|
-4.13 |
-4.91 |
|
PLRPQSSSK |
10.03
|
-0.83 |
-1.61 |
|
SGSPSKPGN |
11.93
|
-2.32 |
-3.10 |
| P36119 |
TRPTVQPSN |
12.04
|
-2.21 |
-2.99 |
|
TTRPTVQPS |
12.12
|
-2.99 |
-3.77 |
| P53046 |
PPTPKSAGH |
11.62
|
-0.98 |
-1.76 |
| P40073 |
GYPQQQPSH |
10.97
|
-2.43 |
-3.21 |
| P24583 |
PPQPRKHDK |
8.21
|
-1.54 |
-2.32 |
|
APLPPQPRK |
8.37
|
-3.22 |
-4.00 |
|
PLPPQPRKH |
9.05
|
-4.03 |
-4.81 |
| P39732 |
STRHPSIAP |
11.45
|
-4.37 |
-5.15 |
|
RSPSVSPVR |
11.50
|
-2.37 |
-3.15 |
|
SSRSPSVSP |
12.81
|
-2.55 |
-3.33 |
| P21268 |
LSKPISPPP |
10.55
|
-3.91 |
-4.69 |
|
KPISPPPSL |
11.55
|
-4.00 |
-4.78 |
|
LNLSKPISP |
12.48
|
-2.64 |
-3.42 |
| P40091 |
PSHPHHNSR |
10.10
|
-4.74 |
-5.52 |
|
SQNPSHPHH |
10.90
|
-1.86 |
-2.64 |
|
QNPSHPHHN |
12.36
|
-1.24 |
-2.02 |
| P40450 |
SSPKLFPRL |
8.24
|
-4.56 |
-5.34 |
|
PPLPESLSM |
8.64
|
-3.57 |
-4.35 |
|
SSSPKLFPR |
9.25
|
-3.70 |
-4.48 |
| P32917 |
SRFPPYSPL |
8.33
|
-2.66 |
-3.44 |
|
TDYLPQHPH |
8.67
|
-3.60 |
-4.38 |
|
PYSPLLPPF |
9.03
|
-4.70 |
-5.48 |
| P25376 |
NDRPSSQPH |
8.33
|
-2.51 |
-3.29 |
|
DRPSSQPHL |
12.01
|
-1.62 |
-2.40 |
|
PSSQPHLGY |
12.68
|
-2.76 |
-3.54 |
| P40020 |
MSLPVTPVK |
9.08
|
-3.98 |
-4.76 |
|
PSIPVEHSN |
9.19
|
-6.27 |
-7.05 |
|
ISLPPYLSP |
9.47
|
-3.74 |
-4.52 |
| P41832 |
GVIPPAPPM |
9.67
|
-4.60 |
-5.38 |
|
PPPPPPPPM |
9.82
|
-3.49 |
-4.27 |
|
PPPPPMALF |
10.07
|
-4.32 |
-5.10 |
| P16892 |
EGEPIPPSF |
10.49
|
-4.58 |
-5.36 |
|
HDPNDEPEG |
12.93
|
-2.67 |
-3.45 |
| P53947 |
PFNPIQDPF |
11.19
|
-5.09 |
-5.87 |
|
SPFNPIQDP |
12.82
|
-1.83 |
-2.61 |
| Q12114 |
SEPVGTPNI |
12.92
|
-1.30 |
-2.08 |
| P31374 |
PERPSFRQP |
7.49
|
-6.42 |
-7.20 |
|
NKKPGTPVF |
9.00
|
-3.86 |
-4.64 |
|
TKPPPPLDF |
9.82
|
-3.85 |
-4.63 |
| Q12753 |
FSIPQSPPL |
9.06
|
-4.53 |
-5.31 |
|
NDLPDTSPM |
10.06
|
-1.67 |
-2.45 |
|
PRMPKTGSR |
10.29
|
-3.63 |
-4.41 |
| P34250 |
HSKKPSNPP |
9.39
|
-2.57 |
-3.35 |
|
LYPKEPPAR |
10.26
|
-3.51 |
-4.29 |
|
EPKPAYVPP |
10.73
|
-3.74 |
-4.52 |
| P14681 |
SDEPEYPPL |
9.98
|
-4.72 |
-5.50 |
|
HDPSDEPEY |
11.57
|
-2.61 |
-3.39 |
| P53950 |
APLLPLPSL |
9.73
|
-3.77 |
-4.55 |
|
PNGAPLRRY |
10.38
|
-1.76 |
-2.54 |
|
TPPAPLLPL |
11.42
|
-2.98 |
-3.76 |
|
