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Matrix information:
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ADAN-name: FUS1_1PWT-25.PDB
Scoring matrix: FUS1_1PWT-25_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 14.9
Foldx random average score for Saccharomyces cerevisiae: 13.745 Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
Proteins belonging to other specie: 0
Nš of interactions described: 47
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
Total fragments: 3207038
Proteins after random average filtering: 7178
Total fragments: 1354464
Proteins after disorder filtering: 4431
Total fragments: 78098
Proteins after pattern filtering: 2186
Total fragments: 14036
Proteins after MINT filtering: 22
Total fragments: 199
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAAAA |
14.90
|
7.24 |
0.00 |
| Best peptides |
RKRPWYPAY |
0.00
|
1.44 |
-5.79 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P36119 |
TRPTVQPSN |
12.27
|
0.73 |
-6.51 |
|
TTRPTVQPS |
12.85
|
1.73 |
-5.51 |
| P53950 |
PNGAPLRRY |
9.84
|
-0.89 |
-8.13 |
|
PNPSIPSAS |
10.34
|
1.43 |
-5.81 |
|
NPNGAPLRR |
10.40
|
-0.54 |
-7.78 |
| P40073 |
DGYPQQQPS |
12.71
|
1.82 |
-5.42 |
| P24583 |
NAPLPPQPR |
10.32
|
-0.21 |
-7.45 |
|
RANAPLPPQ |
10.46
|
0.59 |
-6.65 |
|
PLPPQPRKH |
10.97
|
-1.80 |
-9.04 |
| P53947 |
PFNPIQDPF |
11.33
|
0.80 |
-6.44 |
|
ASPFNPIQD |
13.55
|
1.54 |
-5.70 |
| P34250 |
LYPKEPPAR |
7.60
|
0.16 |
-7.08 |
|
SKKPSNPPS |
8.16
|
-0.77 |
-8.01 |
|
ALYPKEPPA |
9.10
|
0.88 |
-6.36 |
| P53046 |
TPPTPKSAG |
11.05
|
1.36 |
-5.88 |
|
QLSTPPTPK |
11.11
|
-0.64 |
-7.88 |
|
PPTPKSAGH |
13.65
|
2.59 |
-4.65 |
| Q12280 |
VTPPLRPQS |
9.34
|
-1.10 |
-8.34 |
|
PLRPQSSSK |
10.75
|
1.97 |
-5.27 |
|
NVTPPLRPQ |
11.47
|
0.90 |
-6.34 |
| P39732 |
RHPSIAPPS |
10.99
|
0.45 |
-6.79 |
|
STRHPSIAP |
11.97
|
2.32 |
-4.92 |
|
RSPSVSPVR |
12.10
|
-0.05 |
-7.29 |
| P40091 |
SQNPSHPHH |
12.27
|
0.49 |
-6.75 |
|
VTWDPSSPS |
12.50
|
1.59 |
-5.65 |
|
PSHPHHNSR |
13.31
|
-0.17 |
-7.41 |
| P40450 |
SSPKLFPRL |
8.90
|
-1.52 |
-8.76 |
|
SSSPKLFPR |
9.38
|
0.79 |
-6.45 |
|
KLPQLPPPP |
9.72
|
-2.68 |
-9.92 |
| P25376 |
NDRPSSQPH |
11.74
|
2.43 |
-4.80 |
|
PSSQPHLGY |
12.73
|
0.33 |
-6.91 |
|
DRPSSQPHL |
13.42
|
0.64 |
-6.60 |
| P41832 |
PAPPMMPAS |
7.92
|
0.40 |
-6.84 |
|
PPPPPPPPM |
9.12
|
-1.44 |
-8.68 |
|
VIPPAPPMM |
9.90
|
-1.47 |
-8.71 |
| Q03466 |
SSVPMAPDT |
12.61
|
1.57 |
-5.67 |
|
GSSVPMAPD |
13.72
|
2.38 |
-4.86 |
| P31374 |
FRKTKPPPP |
8.83
|
-2.61 |
-9.85 |
|
RKTKPPPPL |
9.42
|
-1.12 |
-8.36 |
|
QPRLPSTAS |
10.10
|
3.20 |
-4.04 |
| P32917 |
SRFPPYSPL |
8.20
|
-1.76 |
-9.00 |
|
YLPQHPHRT |
9.88
|
-1.58 |
-8.82 |
|
PYSPLLPPF |
10.59
|
-0.74 |
-7.98 |
| P40020 |
SLPPYLSPQ |
7.95
|
-1.76 |
-9.00 |
|
VLPPLPFPL |
8.27
|
-2.47 |
-9.71 |
|
DRPPPLTPE |
9.19
|
0.59 |
-6.65 |
| P16892 |
DPNDEPEGE |
12.08
|
2.02 |
-5.21 |
|
NDEPEGEPI |
13.18
|
2.20 |
-5.04 |
|
EPEGEPIPP |
13.44
|
1.83 |
-5.41 |
| Q12114 |
KSEPVGTPN |
13.68
|
0.94 |
-6.29 |
| P21268 |
SKPISPPPS |
9.71
|
-0.77 |
-8.01 |
|
LSKPISPPP |
12.07
|
1.01 |
-6.23 |
|
KPISPPPSL |
13.64
|
0.87 |
-6.37 |
| Q12753 |
SINSPRMPK |
8.49
|
-0.92 |
-8.16 |
|
MIKPKGRPS |
8.82
|
0.51 |
-6.73 |
|
HRYPPMAPT |
9.33
|
0.14 |
-7.10 |
| P14681 |
SDEPEYPPL |
9.25
|
0.42 |
-6.82 |
|
HDPSDEPEY |
11.59
|
1.36 |
-5.88 |
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