ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1PWT-21.PDB
Scoring matrix: FUS1_1PWT-21_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAGGAAAA
Foldx wt ligand score: 19.18
Foldx random average score for Saccharomyces cerevisiae: 16.899

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3199860
Proteins after random average filtering: 7178
 Total fragments: 1954257
Proteins after disorder filtering: 4454
 Total fragments: 78590
Proteins after pattern filtering: 1818
 Total fragments: 4994
Proteins after MINT filtering: 20
 Total fragments: 70


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAGGAAAA

19.18

-1.10

0.00

Best peptides

EWRFGRPTWH

0.00

0.14

1.24

         
Interactors      
Q12280

PLRPQSSSKI

10.74

-5.62

-4.52

PSKPGNNNSY

13.59

-3.43

-2.33

VTPPLRPQSS

15.39

-3.83

-2.73

P31374

NISPERPSFR

9.29

-6.13

-5.03

VFPNLDPTHS

13.02

-5.02

-3.92

PPSPDQENHI

14.68

-4.28

-3.18

P36119

TRPTVQPSNQ

14.68

-3.50

-2.40

RPTVQPSNQS

15.73

-3.94

-2.84

P40073

GYPQQQPSHT

13.11

-4.11

-3.01

P24583

PPQPRKHDKT

14.14

-2.59

-1.49

APLPPQPRKH

14.22

-4.99

-3.89

PLPPQPRKHD

15.72

-4.50

-3.40

P39732

HPSIAPPSKL

13.12

-5.08

-3.98

RSPSVSPVRT

14.95

-4.00

-2.90

SPSVSPVRTT

16.11

-3.15

-2.05

P40091

TWDPSSPSSV

13.80

-4.08

-2.98

SQNPSHPHHN

14.17

-3.20

-2.10

SPASSPVTWD

15.38

-1.90

-0.80

P40450

SSPKLFPRLS

13.49

-3.74

-2.64

PPLPESLSMN

14.44

-4.18

-3.08

PPPPLPQSLL

15.15

-5.25

-4.15

P32917

DYLPQHPHRT

10.75

-3.64

-2.54

PQHPHRTSSL

14.18

-3.22

-2.12

YLPQHPHRTS

16.19

-3.64

-2.54

P25376

DRPSSQPHLG

15.30

-3.97

-2.87

P40020

SEEPTSPTRQ

9.96

-5.02

-3.92

TSAPSIPVEH

12.67

-3.95

-2.85

EEPTSPTRQV

13.77

-2.96

-1.86

P41832

PPLPSVLSSS

16.26

-2.34

-1.24

Q12114

SEPVGTPNIE

14.25

-4.78

-3.68

Q03466

PMAPDTFNVK

13.00

-5.04

-3.94

SVPMAPDTFN

13.56

-5.02

-3.92

P53046

PPTPKSAGHT

15.87

-4.12

-3.02

P53947

NPIQDPFTDN

15.67

-1.53

-0.43

FNPIQDPFTD

16.66

-4.59

-3.49

Q12753

IKPKGRPSTT

12.03

-4.61

-3.51

PRMPKTGSRQ

12.84

-4.48

-3.38

RYPPMAPTTV

12.93

-3.74

-2.64

P34250

SSNPDLPTAL

12.70

-4.26

-3.16

LYPKEPPARK

12.88

-5.12

-4.02

P53950

PSIPSASTST

12.65

-3.05

-1.95

SNPNGAPLRR

14.84

-4.63

-3.53

NPNGAPLRRY

15.95

-2.59

-1.49

P40210

EVDPTEPQTN

15.39

-5.10

-4.00

VDPTEPQTND

16.38

-3.41

-2.31

PTEPQTNDSE

16.74

-0.41

0.69

 


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