ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1PWT-20.PDB
Scoring matrix: FUS1_1PWT-20_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 13.98
Foldx random average score for Saccharomyces cerevisiae: 15.943

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3207038
Proteins after random average filtering: 7178
 Total fragments: 1339343
Proteins after disorder filtering: 4566
 Total fragments: 90523
Proteins after pattern filtering: 2045
 Total fragments: 8754
Proteins after MINT filtering: 22
 Total fragments: 107


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

13.98

1.07

0.00

Best peptides

FRPRRGRWR

0.00

-0.87

-1.94

         
Interactors      
P36119

TRPTVQPSN

13.96

-0.70

-1.77

P53950

PNGAPLRRY

10.45

-2.36

-3.43

NPSIPSAST

13.32

-0.15

-1.22

SNPNGAPLR

14.35

-0.89

-1.96

P40073

GYPQQQPSH

11.96

-2.12

-3.19

P24583

LPPQPRKHD

12.04

-3.40

-4.47

APLPPQPRK

12.45

-2.45

-3.52

PPQPRKHDK

14.78

-0.73

-1.80

P53947

FNPIQDPFT

12.34

0.63

-0.44

PFNPIQDPF

15.32

-0.72

-1.79

P34250

PKEPPARKS

12.38

-3.66

-4.73

ALYPKEPPA

15.19

-1.99

-3.06

KPSNPPSSG

15.69

-2.95

-4.02

P53046

PPTPKSAGH

12.72

-0.71

-1.78

TPPTPKSAG

13.46

-0.98

-2.05

Q12280

NVTPPLRPQ

12.11

-1.49

-2.56

YSGSPSKPG

12.67

-0.10

-1.17

PLRPQSSSK

12.91

-2.11

-3.18

P39732

RSPSVSPVR

14.76

-0.59

-1.66

RHPSIAPPS

14.88

-0.94

-2.01

STRHPSIAP

15.76

-2.45

-3.52

P40091

PSHPHHNSR

11.57

-1.73

-2.80

NPSHPHHNS

13.36

-1.44

-2.51

SQNPSHPHH

13.53

-1.41

-2.48

P40450

PPLPESLSM

11.66

-2.62

-3.69

SSSPKLFPR

12.07

0.86

-0.21

PKLFPRLSS

12.09

-3.32

-4.39

P25376

DRPSSQPHL

13.16

-2.33

-3.40

PSSQPHLGY

13.33

-0.51

-1.58

NDRPSSQPH

14.57

1.69

0.62

P41832

PPPPMALFG

11.15

-0.99

-2.06

PPPPPVPAK

14.16

-2.33

-3.40

PPAPPMMPA

14.42

-3.13

-4.20

Q03466

VPMAPDTFN

14.21

-1.53

-2.60

P31374

FEQPRLPST

10.01

-0.84

-1.91

SPERPSFRQ

10.45

-1.90

-2.97

NISPERPSF

10.81

-2.16

-3.23

P32917

LPQHPHRTS

10.58

-4.81

-5.88

IPPKVAPFG

10.76

-1.49

-2.56

DYLPQHPHR

11.93

-2.71

-3.78

P40020

SEEPTSPTR

13.36

-0.67

-1.74

RVLPPLPFP

13.75

-4.60

-5.67

ISLPPYLSP

14.80

-2.86

-3.93

P16892

YHDPNDEPE

14.90

0.25

-0.82

P40210

EVDPTEPQT

15.46

0.53

-0.54

Q12114

KSEPVGTPN

14.51

-0.02

-1.09

Q12753

MIKPKGRPS

9.47

-3.63

-4.70

INSPRMPKT

11.15

-1.98

-3.05

PRMPKTGSR

11.20

-2.33

-3.40

P14681

YHDPSDEPE

15.21

0.37

-0.70

 


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